Results 151 to 160 of about 74,447 (392)

Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor, Safiya Al Yazeedi, Janaeya Zuri Baher, Chung Cheung, Don D. Sin, Emmanuel Twumasi Osei   +5 more
wiley   +1 more source

THE N- AND C-TERMINAL END GROUPS OF HAIR KERATIN [PDF]

, 1959
M. F. Kerr, C. Godin
openalex   +1 more source

Antitumor lectin Sclerotium rolfsii (SRL) induces apoptosis in human colon cancer cells by activation of multiple signaling pathways; A microarray analysis [PDF]

, 2015
Background: TF antigen specific Sclerotium rolfsii lectin (SRL) inhibits human colon epithelial cancer HT29 cell growth by induction of apoptosis through cell surface binding and has tumor suppressing effect in vivo as reported earlier.
Anupama, S, Barkeer, S, Deepak, SA, Guha, N, Inamdar, SR, Padmanaban, A, Swamy, MB, Vishwanathreddy, H, Yu, LG   +8 more
core  

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source

Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces

Stem Cells International, 2015
Human mesenchymal stem cells (hMSCs) have shown great potential for therapeutic purposes. However, the low frequencies of hMSCs in the body and difficulties in expanding their numbers in vitro have limited their clinical use.
Pietradewi Hartrianti, Ling Ling, Lyn Mei Ming Goh, Kok Seng Amos Ow, Rebekah Margaret Samsonraj, Wan Ting Sow, Shuai Wang, Victor Nurcombe, Simon M. Cool, Kee Woei Ng   +9 more
doaj   +1 more source

Targeting MAN1B1 potently enhances bladder cancer antitumor immunity via deglycosylation of CD47

Cancer Communications, EarlyView.
Abstract Background Only a few bladder cancer patients benefit from anti‐programmed cell death protein 1/programmed cell death ligand 1 immunotherapy. The cluster of differentiation 47 (CD47) plays an important role in tumor immune evasion. CD47 is a highly glycosylated protein, however, the mechanisms governing CD47 glycosylation and its potential ...
Jie Zhang, Chen Zhang, Ruichen Zang, Weiwu Chen, Yining Guo, Haofei Jiang, Jing Le, Kunyu Wang, Haobo Fan, Xudong Wang, Sisi Mo, Peng Gao, Wenhao Guo, Xinrong Jiang, Fengbin Gao, Junming Jiang, Juyan Zheng, Yuxing Chen, Yicheng Chen, Yanlan Yu, Guoqing Ding   +20 more
wiley   +1 more source

Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

Advanced Science
Keratins are an integral part of cell structure and function. Here, it is shown that ectopic expression of a truncated isoform of keratin 81 (tKRT81) in breast cancer is upregulated in metastatic lesions compared to primary tumors and patient‐derived ...
Diane S. Kang, Aidan Moriarty, Yiru Jess Wang, Amal Thomas, Jia Hao, Bret A. Unger, Remi Klotz, Shamim Ahmmed, Yonatan Amzaleg, Stuart Martin, Siva Vanapalli, Ke Xu, Andrew Smith, Keyue Shen, Min Yu   +14 more
doaj   +1 more source

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Hydrolyse des Keratins aus Horn und aus Wolle [PDF]

, 1907
Emil Abderhalden, Arthur Voitinovici
openalex   +1 more source

Pathological Disulfide Bond Crosslinking: Molecular Insights into Amyloidogenesis and Diseases Progression

ChemBioChem, EarlyView.
This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang, Nataliia Lukianenko, Ja‐Hyun Baik, Yun Kyung Kim, Sungsu Lim   +4 more
wiley   +1 more source