Results 191 to 200 of about 28,856 (299)

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

open access: yesActa Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry   +27 more
wiley   +1 more source

Affinity Proteomics‐Based Non‐Invasive Detection of Clinically Significant Liver Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Using UK Biobank proteomic data, we identified a five‐protein score reflecting hepatic stellate cell activation and hepatocellular injury that predicts major adverse liver outcomes and clinically significant fibrosis, with consistent performance validated in two independent cohorts (patients with HIV and alpha1‐antitrypsin deficiency).
Sriram Balasubramani   +14 more
wiley   +1 more source

Emergence of Ophidiomyces ophidiicola, Nannizziopsis barbatae and Paranannizziopsis in free‐ranging Australian reptiles

open access: yesAustralian Veterinary Journal, EarlyView.
Emerging fungal diseases pose a threat to reptiles globally. Increasing detections of onygenalean fungi, particularly Ophidiomyces ophidiicola, Nannizziopsis spp. and Paranannizziopsis spp. in clinically diseased free‐ranging reptiles, indicate likely ongoing spread within wild reptile populations.
RG Butcher   +10 more
wiley   +1 more source

Cholangiocarcinoma in a central bearded dragon (Pogona vitticeps): A case report

open access: yesAustralian Veterinary Journal, EarlyView.
Cholangiocarcinoma is an uncommon malignant epithelial tumour of the biliary tract in reptiles and is rarely reported in central bearded dragons (Pogona vitticeps). This case report describes a 7‐year‐old male central bearded dragon in which a nonspecific coelomic opacity was incidentally detected during a routine clinical examination.
M Mikiewicz   +2 more
wiley   +1 more source

Nail Dystrophy Treated With Marigold Therapy in a Patient With Epidermolysis Bullosa Simplex

open access: yes
Australasian Journal of Dermatology, EarlyView.
Aalia Syed   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy