A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis +3 more
wiley +1 more source
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry +27 more
wiley +1 more source
Mass spectrometry-based proteomics delivers in-depth proteome profiling of FFPE lung cancer biopsies from single glass slides. [PDF]
Berkovska O +8 more
europepmc +1 more source
Hair Degradation Patterns in Aquatic and Soil Environments
ABSTRACT Hair is a biological material that can provide information in archaeology and forensics. Previous studies have mainly examined changes occurring post‐mortem. In this study, we focused on hair pulled out ante‐mortem. The aim of the study was to identify patterns in the degradation of hair in water and soil.
Katarzyna Palacz‐Ziółek +3 more
wiley +1 more source
Integrated transcriptome and proteome analysis identifies keratins as key regulators of corneal scarring in a murine model. [PDF]
Zhou T, Cai Y, Fang F, Cai X, Fu Y.
europepmc +1 more source
Tongue and Glottis Morphology of Cathartes aura and the Secret of Its Functional Adaptation
ABSTRACT Cathartes aura, commonly known as the Turkey vulture, is a scavenger bird belonging to the family Cathartidae that is widely distributed throughout the Americas and classified as a New World vulture. Its diet primarily consists of small‐sized carcasses, predominantly of wild animals.
Jean Caio Figueiredo de Almeida +5 more
wiley +1 more source
Convergent Evolution of Cysteine-Rich Keratins in Horny Teeth of Jawless Vertebrates and in Cornified Skin Appendages of Amniotes. [PDF]
Sachslehner AP, Eckhart L.
europepmc +1 more source
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong +14 more
wiley +1 more source
Prevention of Hair Heat Damage via Thermoresponsive Organic Silicon-Modified Keratin. [PDF]
Li C, Li J, Chang K, Wang J.
europepmc +1 more source
Feasibility and workflow analysis of confocal microscopy in robot‐assisted prostatectomy
Objectives To assess the diagnostic accuracy, workflow feasibility, and downstream compatibility of fluorescence confocal microscopy (Histolog® Scanner [HS]; SamanTree Medical SA, Lausanne, Switzerland) compared with frozen section (FS) for intraoperative margin evaluation (IME) during nerve‐sparing robot‐assisted radical prostatectomy (RARP). Patients
Kristijan Skok +11 more
wiley +1 more source

