Our study presents a novel approach to localized cancer therapy by developing mouse serum albumin (MSA)‐coated paclitaxel (PTX)‐loaded gelatin nanoparticles (MSA@PTX‐loaded GNPs) as a stealth drug delivery system. Given the challenges of nanoparticle‐based chemotherapy, including rapid opsonization and limited drug accumulation at tumor sites, our work
Md. Annur Sadman+10 more
wiley +1 more source
The feather's multi-functional structure across nano to macro scales inspires hierarchical design. [PDF]
Hendrickx-Rodriguez S, Lentink D.
europepmc +1 more source
Abstract Although relatively rare, metaplastic breast cancer responds poorly to traditional therapies compared to other subtypes. Accordingly, there is a need for novel animal models to understand its pathogenesis and plasticity. Since alterations in PIK3CA and TP53 genes are common in metaplastic breast cancer, we generated a mouse model of ...
Khoa A Nguyen+11 more
wiley +1 more source
Clothomics: a practical guide to understand the opportunities and challenges of omics-based methods in archaeological cloth research. [PDF]
Viñas-Caron LC, Brandt LØ.
europepmc +1 more source
Teratoid Hepatoblastoma: Clinicopathologic Features and Outcomes
ABSTRACT Background Teratoid hepatoblastoma (HB) is a rare histologic subtype of the most common pediatric liver cancer. Understanding of the clinicopathologic features and outcomes of patients with this disease is currently limited. Methods Multi‐institution, retrospective chart review was conducted to compare 20 children with teratoid HB to 129 ...
Brian T. Hickner+8 more
wiley +1 more source
miR-195-5p Suppresses KRT80 Expression Inducing Cell Cycle Arrest in Colon Cancer. [PDF]
Piccinno E+6 more
europepmc +1 more source
Structural Variability of Pfam Domains Based on Alphafold2 Predictions
ABSTRACT Understanding the biological functions of proteins is one of the main goals of functional genomics. Such understanding will help control and manipulate biological processes to enhance desirable traits, including improved abiotic and biotic stress resistance in humans, animals, plants, and microbes.
Elly Poretsky+2 more
wiley +1 more source
Knockdown of Keratin 6 Within Arsenite-Transformed Human Urothelial Cells Decreases Basal/Squamous Expression, Inhibits Growth, and Increases Cisplatin Sensitivity. [PDF]
Nargis N, Sens DA, Mehus AA.
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Alkali Solubilization of Chichken Feather Keratin
Yasutoyo NAGAI, Tetsusaburo NISHIKAWA
openalex +2 more sources
Insights Into Effects of Natural Bioactive Components on Inflammatory Diseases in Respiratory Tract
ABSTRACT The increasing prevalence of inflammatory diseases in the respiratory tract worldwide has raised concerns, and due to its high prevalence and poor prognosis, it remains a clinical focus and research hotspot. These inflammatory diseases include airway inflammation, asthma, bacterial antigens‐induced tonsil epithelial inflammation, chronic ...
Jincan Luo+4 more
wiley +1 more source