Cell and Gene Therapy in Equine Ocular Disease. [PDF]
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Young KAS, Schnabel LV, Gilger BC.
europepmc +2 more sources
A serious adverse surgical event: Management of suspected HSV-1 keratitis in a donor cornea. [PDF]
PurposeTo describe the management of a serious adverse event in a patient undergoing penetrating keratoplasty (PK).Case reportA 68-year-old man underwent PK for an aphakic bullous keratopathy following previous complicated cataract surgery.
Chen, Jern Y +3 more
core +3 more sources
Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]
Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N +4 more
core +3 more sources
Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa. [PDF]
Previously we reported that corneal epithelial barrier function against Pseudomonas aeruginosa was MyD88-dependent. Here, we explored contributions of MyD88-dependent receptors using vital mouse eyes and confocal imaging. Uninjured IL-1R (-/-) or TLR4 (-/
Evans, David +5 more
core +3 more sources
Bilateral pseudo-dendritic keratitis in infancy can be due to tyrosinemia, a rare metabolic disorder. Ocular involvement may be the earliest presenting manifestation of this disease. Early diagnosis is essential because dietary modifications can result in complete reversal of the manifestations of this disorder.
Gokhale Nikhil +3 more
openaire +3 more sources
High-Risk Corneal Graft Rejection in the Setting of Previous Corneal Herpes Simplex Virus (HSV)-1 Infection [PDF]
Acknowledgments The authors thank M. Robertson and R. Fordyce for technical support during the duration of the study. The work performed in Aberdeen was supported by grant from Action Medical Research UK (SP4328; London, England, UK), NHS Grampian ...
Amescua, Guillermo +7 more
core +1 more source
Acute Herpetic Keratitis: What is the Role for Ganciclovir Ophthalmic Gel? [PDF]
Herpes simplex keratitis (HSK) is a major cause of corneal blindness in the world. Following the primary infection, the virus enters into a latent phase.
Hamrah, Pedram, Sahin, Afsun
core +3 more sources
Collection of corneal impression cytology directly on a sterile glass slide for the detection of viral antigen: An inexpensive and simple technique for the diagnosis of HSV epithelial keratitis – A pilot study [PDF]
Background: Herpes simplex keratitis (HSK) is a sight threatening ocular infection and occurs worldwide. A prompt laboratory diagnosis is often very useful. Conventional virology techniques are often expensive and time consuming.
Sreedharan Athmanathan +2 more
core +1 more source
High-risk corneal allografts : A therapeutic challenge [PDF]
Peer reviewedPublisher ...
Forrester, John V +4 more
core +1 more source
In Vivo Confocal Microscopy Cellular Features of Host and Organism in Bacterial, Fungal, and Acanthamoeba Keratitis. [PDF]
PURPOSE: To determine cellular features of fungal (FK), Acanthamoeba (AK), and bacterial keratitis (BK) using HRT3 in vivo confocal microscopy (IVCM). DESIGN: Prospective observational cross-sectional study.
Burton, Matthew J +8 more
core +1 more source

