Impaired fas-fas ligand interactions result in greater recurrent herpetic stromal keratitis in mice [PDF]
, 2015 Herpes simplex virus-1 (HSV-1) infection of the cornea leads to a potentially blinding condition termed herpetic stromal keratitis (HSK). Clinical studies have indicated that disease is primarily associated with recurrent HSK following reactivation of a ...
Chelsea R. Del Rosso +7 more
core +4 more sources
The Role of Decorin in the Ocular Surface: Structure, Function, and Therapeutic Potential
Proteoglycan Research, Volume 3, Issue 3, July 2025.ABSTRACT The ocular surface, comprising the cornea, conjunctiva, and sclera, relies on a complex extracellular matrix (ECM) for structural support and functional integrity. Decorin (DCN), a small leucine‐rich proteoglycan, a key ECM component involved in collagen fibrillogenesis, growth factor modulation, and cellular regulation, is essential for ...
Kartik Goel +5 more
wiley +1 more source
Polyunsaturated fatty acid-derived lipid mediators and T cell function [PDF]
, 2014 Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
Marelli-Berg, F +3 more
core +3 more sources
Xenotransplantation, Volume 32, Issue 4, July/August 2025.ABSTRACT Xenotransplantation is becoming an emerging field of interest for the treatment of end‐stage heart disease. In fact, the shortage of human heart donors in European countries requires the increasing investigation of alternative strategies such as heart xenotransplantation.
Nicola Pradegan +6 more
wiley +1 more source
PATIENT COMPLIANCE AS AN EFFECTIVENESS FACTOR OF COMPLICATED DENDRITIC HERPETIC KERATITIS TREATMENT
Ukrainian Scientific Medical Youth Journal, 2015 Summary. Every year almost 10 million patients are registered with ophthalmic herpes. Herpetic keratitis is associated with more than 66,8% of the entire cornea pathology, 55,1% of all ulcerative lesions and it causes more than 60% of the corneal ...
D. Pavlenko
doaj
HSV-1 antigens and DNA in the corneal explant buttons of patients with non-herpetic or clinically atypical herpetic stromal keratitis [PDF]
, 2018 Background: Little is known about the role of HSV-1 in keratitis not primarily attributed to herpetic origin. This study therefore aimed to prospectively evaluate the corneal explant buttons of patients with non-herpetic or clinically atypical herpetic ...
Böhnke, Matthias +4 more
core
, 2012 Rosacea is a prevalent chronic cutaneous disorder with variable presentation and severity. Although considered a skin disease, rosacea may evolve the eyes in 58-72% of the patients, causing eyelid and ocular surface inflammation.
Hofling-Lima, Ana Luisa +2 more
core +2 more sources
Cystatin C and lactoferrin concentrations in biological fluids as possible prognostic factors in eye tumor development [PDF]
, 2013 Objectives. To investigate the possible role of cystatin C in eye biological fluids locally and in serum and lactoferrin revealing anti-tumor activity in eye tumor development. Background.
Ananthi S +19 more
core +1 more source
Features of the course of post-COVID-19 primary and recurrent herpetic keratitis
Journal of OphthalmologyPurpose: To assess the features of the course of post-COVID-19 primary and recurrent herpetic keratitis (HK). Material and Methods: Medical records of 70 patients (83 eyes) with post-COVID-19 HK were reviewed.
G.I. Drozhzhyna +2 more
doaj +1 more source
Generation and Regulation of CD8+ Regulatory T Cells [PDF]
, 2014 Research into the suppressive activity of CD4+FoxP3+ T regulatory cells (Treg) has defined a sublineage of CD4+ cells that contribute to self-tolerance and resistance to autoimmune disease. Much less attention has been given to the potential contribution
Cantor, Harvey, Lu, Linrong
core +1 more source