European Journal of Neurology, Volume 33, Issue 5, May 2026.This study investigates four Chinese families with congenital insensitivity to pain with anhidrosis (CIPA). Through next‐generation sequencing, we identified seven NTRK1 variants, including two novel mutations. Functional characterization of five identified missense and indel variants revealed distinct disruptions in the NGF‐TrkA pathway, ranging from ...
Yaqiong Ren +9 more
wiley +1 more source
Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68‐week randomized Phase 3 trial
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 887-899, May 2026.This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Masamoto Murakami +6 more
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Veterinary Ophthalmology, Volume 29, Issue 3, May 2026.ABSTRACT Purpose To compare the incidence of surgical site infections (SSI) following routine ophthalmic soft tissue surgeries in dogs receiving (AB) and not receiving (noAB) postoperative antibiotics. Methods Clinical records of dogs that underwent enucleations, wedge resections, medial canthoplasties, and simple and complicated eyelid surgeries with ...
Ana Cristina Piroth, Claudia Busse
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[Amebic keratitis-keratitis acanthamoeba].
Klinika oczna, 1995 In seventeen patients who suffered of corneal ulcer, and were negative in bacteriological and mycological examinations, parasitological tests were performed between 1990-1992. Acanthamoeba keratitis was diagnosed in one patient with characteristic corneal changes of right eye following trauma. The patient was not a contact lens wearer. The amoeba found
R, Gieryng +4 more
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Veterinary Ophthalmology, Volume 29, Issue 3, May 2026.ABSTRACT Objective To evaluate the clinical efficacy of a newly developed adhesive tissue sealant, gelatinized cornea‐derived decellularized extracellular matrix (Cod‐ECM) for the treatment of stromal ulcers in dogs. Animal Studied This study included 60 eyes of 56 dogs diagnosed with stromal ulcerative keratitis, limited to corneal ulcers involving ...
Su‐Jung Yang +4 more
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Veterinary Radiology &Ultrasound, Volume 67, Issue 3, May 2026.ABSTRACT Radiotherapy for the treatment of sinonasal tumors in dogs is generally well tolerated, but the range of long‐term adverse effects remains poorly understood. In people receiving radiation for head and neck tumors, existing dental disease is a predisposing factor for radiation‐induced oral complications that can lead to worsening periodontal ...
Erin Paul‐Stewart +4 more
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Diagnostic Role of Anterior Segment Optical Coherence Tomography in an Atypical Presentation of Varicella Zoster Virus Interstitial Keratitis: A Case Report. [PDF]
Am J Case RepAlsaggaf K, Jomar DE, Al-Swailem SA.
europepmc +1 more source
Bacterial and fungal keratitis in Northeast Mexico: demographic, predisposing, and microbiological differences among non-contact lens, optical contact lens, and bandage contact lens wearers. [PDF]
Int OphthalmolMohamed-Noriega K +9 more
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Rare fungal keratitis caused by plant pathogens: report of two cases and review of the literature. [PDF]
Front Fungal BiolZhao Z +5 more
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Bridging gaps in corneal ulcer management: Can photoactivated chromophore for infectious keratitis-corneal collagen cross-linking delay or replace therapeutic keratoplasty? [PDF]
World J TransplantAntonopoulou NI +4 more
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