Results 21 to 30 of about 26,868 (188)

Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis

open access: yesCell Discovery, 2022
Keratoconus is a common ectatic corneal disorder in adolescents and young adults that can lead to progressive visual impairment or even legal blindness. Despite the high prevalence, its etiology is not fully understood. In this study, we performed single-
Shengqian Dou   +13 more
doaj   +1 more source

The variability of corneal and anterior segment parameters in keratoconus [PDF]

open access: yes, 2016
Purpose: To analyse, describe and test diverse corneal and anterior segment parameters in normal and keratoconic eyes to better understand the geometry of the keratoconic cornea. Method: 44 eyes from 44 keratoconic patients and 44 eyes from 44 healthy
Cardona Torradeflot, Genís   +3 more
core   +1 more source

Rare single nucleotide variants in COL5A1 promoter do not play a major role in keratoconus susceptibility associated with rs1536482

open access: yesBMC Ophthalmology, 2021
Background Keratoconus is a chronic degenerative disorder of the cornea characterized by thinning and cone-shaped protrusions. Although genetic factors play a key role in keratoconus development, the etiology is still under investigation.
Liubov O. Skorodumova   +13 more
doaj   +1 more source

Scanning-slit topography in patients with keratoconus [PDF]

open access: yes, 2018
L
Flaskó, Zsuzsanna   +4 more
core   +5 more sources

Quantitative comparison of corneal surface areas in keratoconus and normal eyes

open access: yesScientific Reports, 2021
Keratoconus is a highly prevalent corneal disorder characterized by progressive corneal thinning, steepening and irregular astigmatism. To date, pathophysiology of keratoconus development and progression remains debated. In this study, we retrospectively
François-Xavier Crahay   +5 more
doaj   +1 more source

Prevalence of keratoconus in persons with Down syndrome: a review

open access: yesBMJ Open Ophthalmology, 2021
Purpose Keratoconus is a vision-threatening condition, and there is a need for knowledge about the occurrence in subgroups of the population. The progression of the disease can be effectively stopped, and vision may be restored, if keratoconus is ...
Liv Drolsum, Olav Kristianslund
doaj   +1 more source

Advance in Keratoconus Biomechanics

open access: yesTaiyuan Ligong Daxue xuebao, 2022
Keratoconus is a bilateral asymmetric corneal dilatation disease characterized by localized thinning and increased curvature of cornea. The alteration of the mechanical properties occurs earlier than morphological change owing to corneal structure ...
Junchao WEI, Xiaona LI
doaj   +1 more source

Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

open access: yes, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz   +14 more
core   +1 more source

Corneal Volume Measurements with Pentacam for Detection of Keratoconus and Subclinical Keratoconus

open access: yesTürk Oftalmoloji Dergisi, 2013
Pur po se: To estimate the sensitivity and specificity of corneal volume (CV) measurements in discriminating keratoconus and subclinical keratoconus from normal corneas. Ma te ri al and Met hod: Clinical records and Pentacam measurements of ninety-four
Nurullah Çağıl   +5 more
doaj   +1 more source

Corneal stromal demarcation line after collagen cross-linking in corneal ectatic diseases: a review of the literature [PDF]

open access: yes, 2016
Collagen cross-linking (CXL) is a relatively new conservative approach for progressive corneal ectasia, which is able to strengthen corneal tissue reforming new covalent bonds.
SPADEA, LEOPOLDO   +2 more
core   +1 more source

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