Results 31 to 40 of about 23,168 (223)

Rare single nucleotide variants in COL5A1 promoter do not play a major role in keratoconus susceptibility associated with rs1536482

BMC Ophthalmology, 2021
Background Keratoconus is a chronic degenerative disorder of the cornea characterized by thinning and cone-shaped protrusions. Although genetic factors play a key role in keratoconus development, the etiology is still under investigation.
Liubov O. Skorodumova, Alexandra V. Belodedova, Elena I. Sharova, Elena S. Zakharova, Liliia N. Iulmetova, Mukharram M. Bikbov, Emin L. Usubov, Olga P. Antonova, Oksana V. Selezneva, Anastasia Levchenko, Olga Yu Fedorenko, Svetlana A. Ivanova, Raul R. Gainetdinov, Boris E. Malyugin   +13 more
doaj   +1 more source

Quantitative comparison of corneal surface areas in keratoconus and normal eyes

Scientific Reports, 2021
Keratoconus is a highly prevalent corneal disorder characterized by progressive corneal thinning, steepening and irregular astigmatism. To date, pathophysiology of keratoconus development and progression remains debated. In this study, we retrospectively
François-Xavier Crahay, Guillaume Debellemanière, Stephan Tobalem, Wassim Ghazal, Sarah Moran, Damien Gatinel   +5 more
doaj   +1 more source

Prevalence of keratoconus in persons with Down syndrome: a review

BMJ Open Ophthalmology, 2021
Purpose Keratoconus is a vision-threatening condition, and there is a need for knowledge about the occurrence in subgroups of the population. The progression of the disease can be effectively stopped, and vision may be restored, if keratoconus is ...
Liv Drolsum, Olav Kristianslund
doaj   +1 more source

A predictive model for early diagnosis of keratoconus

BMC Ophthalmology, 2020
Background The diagnosis of keratoconus in the early stages of the disease is necessary to initiate an early treatment of keratoconus. Furthermore, to avoid possible refractive surgery that could produce ectasias.
Gracia Castro-Luna, Antonio Pérez-Rueda
doaj   +1 more source

Biocompatibility and Biomechanical Effect of Single Wall Carbon Nanotubes Implanted in the Corneal Stroma: A Proof of Concept Investigation

Journal of Ophthalmology, 2016
Corneal ectatic disorders are characterized by a progressive weakening of the tissue due to biomechanical alterations of the corneal collagen fibers.
Alfredo Vega-Estrada, Joaquin Silvestre-Albero, Alejandra E. Rodriguez, Francisco Rodriguez-Reinoso, Jose A. Gomez-Tejedor, Carmen M. Antolinos-Turpin, Laurent Bataille, Jorge L. Alio   +7 more
doaj   +1 more source

Evaluation of Scheimpflug Tomography Parameters in Subclinical Keratoconus, Clinical Keratoconus and Normal Caucasian Eyes

Türk Oftalmoloji Dergisi, 2018
Objectives: To evaluate tomographic and topographic parameters in subclinical and clinical keratoconus eyes by comparing them with normal eyes in a young Caucasian population. Materials and Methods: This cross-sectional study included 88 normal eyes
Samira Huseynli, Farah Abdulaliyeva
doaj   +1 more source

Advance in Keratoconus Biomechanics

Taiyuan Ligong Daxue xuebao, 2022
Keratoconus is a bilateral asymmetric corneal dilatation disease characterized by localized thinning and increased curvature of cornea. The alteration of the mechanical properties occurs earlier than morphological change owing to corneal structure ...
Junchao WEI, Xiaona LI
doaj   +1 more source

Assessment of the Association between In Vivo Corneal Morphogeometrical Changes and Keratoconus Eyes with Severe Visual Limitation

Journal of Ophthalmology, 2019
Assessing changes suffered by the cornea as keratoconus progresses has proven to be vital for this disease diagnosis and treatment. This study determines the corneal biometric profile in eyes considered as affected by keratoconus (KC) showing severe ...
J. S. Velázquez, F. Cavas, J. Alió del Barrio, D. G. Fernández-Pacheco, J. Alió   +4 more
doaj   +1 more source

Assessment of Visual Quality in Eyes with Forme Fruste Keratoconus and Mild and Moderate Keratoconus Based on Optical Quality Analysis System II Parameters

Journal of Ophthalmology, 2020
Purpose. The study aimed to evaluate the visual quality of forme fruste keratoconus (FFK) and mild and moderate keratoconus by using an optical quality analysis system II (OQAS-II) and to explore the correlation between optical quality parameters and the
Zhonghao Ren, Liyan Xu, Qi Fan, Kaili Yang, Shengwei Ren, Dongqing Zhao   +5 more
doaj   +1 more source

The genetics of keratoconus

Middle East African Journal of Ophthalmology, 2011
Keratoconus (KTCN) is non-inflammatory thinning and anterior protrusion of the cornea that results in steepening and distortion of the cornea, altered refractive error, and decreased vision. Keratoconus is a complex condition of multifactorial etiology. Both genetic and environmental factors are associated with KTCN.
Nowak, Dorota M., Gajecka, Marzena
openaire   +3 more sources