Results 31 to 40 of about 52,806 (298)

Rare single nucleotide variants in COL5A1 promoter do not play a major role in keratoconus susceptibility associated with rs1536482

open access: yesBMC Ophthalmology, 2021
Background Keratoconus is a chronic degenerative disorder of the cornea characterized by thinning and cone-shaped protrusions. Although genetic factors play a key role in keratoconus development, the etiology is still under investigation.
Liubov O. Skorodumova   +13 more
doaj   +1 more source

A multi-ethnic genome-wide association study implicates collagen matrix integrity and cell differentiation pathways in keratoconus

open access: yesCommunications Biology, 2021
Keratoconus is characterised by reduced rigidity of the cornea with distortion and focal thinning that causes blurred vision, however, the pathogenetic mechanisms are unknown.
A. Hardcastle   +61 more
semanticscholar   +1 more source

Quantitative comparison of corneal surface areas in keratoconus and normal eyes

open access: yesScientific Reports, 2021
Keratoconus is a highly prevalent corneal disorder characterized by progressive corneal thinning, steepening and irregular astigmatism. To date, pathophysiology of keratoconus development and progression remains debated. In this study, we retrospectively
François-Xavier Crahay   +5 more
doaj   +1 more source

Prevalence of keratoconus in persons with Down syndrome: a review

open access: yesBMJ Open Ophthalmology, 2021
Purpose Keratoconus is a vision-threatening condition, and there is a need for knowledge about the occurrence in subgroups of the population. The progression of the disease can be effectively stopped, and vision may be restored, if keratoconus is ...
Liv Drolsum, Olav Kristianslund
doaj   +1 more source

Keratoconus detection of changes using deep learning of colour-coded maps

open access: yesBMJ Open Ophthalmology, 2021
Objective To evaluate the accuracy of convolutional neural networks technique (CNN) in detecting keratoconus using colour-coded corneal maps obtained by a Scheimpflug camera. Design Multicentre retrospective study.
Xu Chen   +13 more
semanticscholar   +1 more source

Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]

open access: yes, 2017
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz   +14 more
core   +1 more source

Pediatric keratoconus - Current perspectives and clinical challenges

open access: yesIndian Journal of Ophthalmology, 2021
Keratoconus is an ectatic corneal disease characterized by progressive stromal thinning, irregular astigmatism, and defective vision. It can be unilateral or bilateral with asymmetric presentation. It starts at puberty and either progresses rapidly to an
V. Anitha   +5 more
semanticscholar   +1 more source

Corneal Volume Measurements with Pentacam for Detection of Keratoconus and Subclinical Keratoconus

open access: yesTürk Oftalmoloji Dergisi, 2013
Pur po se: To estimate the sensitivity and specificity of corneal volume (CV) measurements in discriminating keratoconus and subclinical keratoconus from normal corneas. Ma te ri al and Met hod: Clinical records and Pentacam measurements of ninety-four
Nurullah Çağıl   +5 more
doaj   +1 more source

Advance in Keratoconus Biomechanics

open access: yesTaiyuan Ligong Daxue xuebao, 2022
Keratoconus is a bilateral asymmetric corneal dilatation disease characterized by localized thinning and increased curvature of cornea. The alteration of the mechanical properties occurs earlier than morphological change owing to corneal structure ...
Junchao WEI, Xiaona LI
doaj   +1 more source

Biocompatibility and Biomechanical Effect of Single Wall Carbon Nanotubes Implanted in the Corneal Stroma: A Proof of Concept Investigation

open access: yesJournal of Ophthalmology, 2016
Corneal ectatic disorders are characterized by a progressive weakening of the tissue due to biomechanical alterations of the corneal collagen fibers.
Alfredo Vega-Estrada   +7 more
doaj   +1 more source

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