Obesity-Associated Abdominal Elephantiasis
Abdominal elephantiasis is a rare entity. Abdominal elephantiasis is an uncommon, but deformative and progressive cutaneous disease caused by chronic lymphedema and recurrent streptococcal or Staphylococcus infections of the abdominal wall.
Ritesh Kohli+2 more
doaj +1 more source
A drug will not function unless it is bound to a receptor: a longstanding confusion in basic pharmacology [PDF]
The disparity between the general definition of a ‘drug’ and the wide-spread mechanism of actions of receptor-dependent drugs may often mislead to believe that a drug-receptor interaction is always indispensable for a drug to exert its action. This short
Saha, Partha S.
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Successful Treatment of an Adult with Atopic Dermatitis and Lamellar Ichthyosis Using Dupilumab
Faisal K Binkhonain, Sara Aldokhayel, Hessah BinJadeed, Abdulaziz Madani Dermatology Department, College of Medicine, King Saud University, Riyadh, Saudi ArabiaCorrespondence: Abdulaziz Madani, Dermatology Department, King Saud University, Riyadh, 7805 ...
Binkhonain FK+3 more
doaj
pH-Sensitive Mucoadhesive Film-Forming Gels and Wax-Film Composites Suitable for Topical and Mucosal Delivery of Molecules [PDF]
The present invention relates to pH-sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules of interest, namely active pharmaceuticals.
Jay, Michael, Mumper, Russell J.
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Antimicrobial and anti-inflammatory activity of chitosan-alginate nanoparticles: a targeted therapy for cutaneous pathogens. [PDF]
Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver ...
Blecher-Paz, Karin+10 more
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Hyper IgE Syndromes: Understanding, Management, and Future Perspectives: A Narrative Review
ABSTRACT Background and Aim Hyper IgE syndromes (HIES) are rare primary immunodeficiency characterized by susceptibility to specific infections, eczema, and elevated IgE levels. Pathogenic mutations in STAT3, IL6R, IL6ST, ERBB2IP, PGM3, ZNF431, SPINK5, TGFBR1/2, and CARD11 have been identified as genetic factors contributing to phenotypes of HIES lead ...
Mohammad Salehi+6 more
wiley +1 more source
Combination of 30% salicylic acid peels and mechanical comedo extraction for the treatment of Favre-Racouchot syndrome [PDF]
No abstract ...
Anargyros Kouris+5 more
core +1 more source
Abstract Acral peeling skin syndrome (APSS; MIM 609796) is a rare genodermatosis characterized by painless focal cutaneous exfoliation of the dorsal hands and feet, typically displaying autosomal recessive inheritance. While cases associated with a founder mutation in TGM5 are relatively common in European Caucasian populations, no APSS cases have been
Toshihide Higashino+4 more
wiley +1 more source
Multidisciplinary evaluation of preschool children in a military psychiatry clinic: a 10-year comparison and a brief outcome study. [PDF]
A little over a decade ago, the Child and Adolescent Psychiatry Service at Tripler Army Medical Center opened the Child Study Group (CSG), a multidisciplinary diagnostic team clinic for preschool children.
Lee, B J
core
ABSTRACT The possibility of modulating the treatment regimen regarding dose reduction (de‐escalation) or dose augmentation (escalation) in psoriasis biological treatment has been of increasing interest. De‐escalation strategies include reducing the single therapeutic dose, the mg/kg ratio or the number of injections, or dose‐spacing (D‐S), that is ...
Luca Mastorino+7 more
wiley +1 more source