Clinical benefit and tolerance profile of a keratolytic and hydrating shampoo in subjects with mild to moderate psoriasis. Results from a double‐blind, randomized, vehicle‐controlled study [PDF]
Journal of Cosmetic Dermatology, 2023 Scalp psoriasis frequently goes with other disease location and may lead to a significant burden and impairment of quality of life (QoL). Adherence to local treatments is a frequent problem.
Philippe Massiot +10 more
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Urea in Dermatology: A Review of its Emollient, Moisturizing, Keratolytic, Skin Barrier Enhancing and Antimicrobial Properties [PDF]
Dermatologic Therapy, 2021 Urea is a hygroscopic molecule (capable of absorbing water) present in the epidermis as a component of the natural moisturizing factor (NMF) and is essential for the adequate hydration and integrity of the stratum corneum.
Jaime Piquero‐Casals +5 more
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Acta medica Philippina, 2022 Background Pityriasis versicolor is a common fungal infection of the superficial skin layer caused by Malassezia furfur, a normal commensal in the skin.
Rowena Natividad F Genuino +4 more
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Effect of Keratolytic Drugs on Oral Hyperkeratosis in Syrian Hamsters [PDF]
Journal of Dental Research, 1966 SYNOPSIS IN INTERLINGUA LE EFFECTO DE PHARMACOS KERATOLYTIC SUPER HYPERKERATOSIS ORAL.—Leslones hyperkeratotic del mucosa oral esseva inducite in albin hamsters syrian per le administration topic de 9,10-dimethyl-l,2-benzanthraceno. Post 6 applicationes de un solution de 20 pro cento de acido salicylic, un significative declino quantitative esseva ...
John A. Capodanno, James R. Hayward
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A Keratolytic Gel Containing Salicylic Acid in Propylene Glycol
Journal of Investigative Dermatology, 1973 Mixtures of propylene glycol and water have been shown to be effective in several types of ichthyosis. A new formulation has been developed which contains a gelling agent, propylene glycol, ethanol, and salicylic acid in distilled water. This gel has been shown to be very effective in removal of thickened stratum corneum in a variety of disorders ...
Howard P. Baden, Joseph C. Alper
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Placebo-Controlled Trial to Determine the Effectiveness of a Urea/Lactic Acid–Based Topical Keratolytic Agent for Prevention of Capecitabine-Induced Hand-Foot Syndrome: North Central Cancer Treatment Group Study N05C5 [PDF]
Journal of Clinical Oncology, 2010 PURPOSE Hand-foot syndrome (HFS) is a dose-limiting toxicity of capecitabine for which no effective preventative treatment has been definitively demonstrated. This trial was conducted on the basis of preliminary data that a urea/lactic acid-based topical
Sherry L. Wolf +10 more
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Keratolytics and Emollients and Their Role in the Therapy of Psoriasis: a Systematic Review [PDF]
Dermatology and Therapy, 2015 Psoriasis is a common chronic disease with significant impairment in quality of life. As there is no cure, it often requires lifelong disease control to minimize the development of skin lesions and to relieve symptoms. The aim of this publication is to systematically review the role of currently used emollients and keratolytics in the treatment of ...
Arnd Jacobi, A. Mayer, Matthias Augustin
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Presentation of acanthosis nigricans as scalp papillomatosis: a case report [PDF]
Journal of Medical Case ReportsBackground Acanthosis nigricans is a skin condition characterized by dark, thickened plaques, typically found in intertriginous regions such as the groin and neck. While commonly associated with obesity and insulin resistance, acanthosis nigricans rarely
Fatemeh Mohaghegh +4 more
doaj +2 more sources
Evidenced-based approach facilitates choosing between different topical compounds in acne vulgaris. [PDF]
J Eur Acad Dermatol VenereolJournal of the European Academy of Dermatology and Venereology, Volume 39, Issue 4, Page 711-712, April 2025.
Nikolakis G, Zouboulis CC.
europepmc +2 more sources
Erythrokeratolysis hiemalis (keratolytic winter erythema): a case report from Denmark [PDF]
Journal of the European Academy of Dermatology and Venereology, 2001 AbstractErythrokeratolysis hiemalis is described as a rare autosomal dominant genodermatosis as first reported from the Oudtshoorn district of Cape Provence in South Africa, among European immigrant families. Sporadic cases have since been identified in other countries, often with a familial link to the Oudtshoorn cluster.
AG Danielsen, K Weismann, H. K. Thomsen
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