Results 211 to 220 of about 3,802 (241)

Cutaneous bioassay of salicylic acid as a keratolytic

International Journal of Pharmaceutics, 2005
Keratolytic efficacy of topical preparations containing salicylic acid was studied in humans utilizing adhesive tape stripping and quantifying SC removal by protein analysis. In combination with tape stripping, squamometry was used to evaluate the influence of salicylic acid on skin surface scaliness and desquamation.
S J, Bashir, F, Dreher, A L, Chew, H, Zhai, C, Levin, R, Stern, H I, Maibach   +6 more
openaire   +2 more sources

Keratolytic winter erythema with facial involvement: a novel presentation

Clinical and Experimental Dermatology, 2009
We present a 23-year-old woman with a diagnosis of keratolytic winter erythema (erythrokeratolysis hiemalis), who developed facial lesions following a traumatic experience. This rare genodermatosis usually affects the palms and soles, and appears as mild erythema and annular scaling. The limbs and trunk can rarely be affected. To our knowledge, this is
C V, Degiovanni, P B J, Farrant, S, Howell, P R, Hull, A, Woollons   +4 more
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Therapy With Keratolytic Gel and Corticosteroid Ointment

Archives of Dermatology, 1975
To the Editor.— I would like to respond to a number of inquiries regarding the use of a keratolytic gel and corticosteroid ointment1in treating generalized psoriasis. The failure of many topically applied agents to clear psoriatic plaques results in part from slow penetration through the hyperkeratotic surface of the skin.
openaire   +1 more source

Antioxidant, Keratolytic, and Hydrating Treatment for Seborrheic Keratoses

Journal of Drugs in Dermatology
Seborrheic keratoses (SKs) are the most common skin lesions to prompt visits to a dermatologist. Patients may be concerned about unsightly appearance, irritation, or the possibility of skin cancer. They frequently ask if there is a topical treatment for these lesions.We sought to determine an effective topical formula to improve the appearance of ...
William, V Stoecker, Jonathan, Kopel, Navin, Geria, Nasim, Nosoudi   +3 more
openaire   +2 more sources

Distribution and Keratolytic Effect of Salicylic Acid and Urea in Human Skin

Skin Pharmacology and Physiology, 1995
Salicylic acid (SA) and urea are widely used in topical preparations. Using a simple tape stripping technique the effect on the binding forces within the stratum corneum and the skin absorption of SA and urea were studied. The degree of stratum corneum removal was recorded by measuring the transmission through the tape with a digital light-measuring ...
M, Lodén, P, Boström, M, Kneczke
openaire   +2 more sources

Erythrokeratolysis hiemalis—Keratolytic winter erythema or 'Oudtshoorn Skin'.

British Journal of Dermatology, 1978
A new autosomal, dominantly inherited epidermal disorder is described in which a spreading dissection of the stratum corneum with redness of the palms and soles occurs as a result of a centrifugal necrobiosis of the Malpighian layer below it. Iis is seen characteristically in winter.
G H, Findlay, J G, Morrison
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‘Keratolytic’ Properties of Benzoyl Peroxide and Retinoic Acid Resemble Salicylic Acid in Man

Skin Pharmacology and Physiology, 2006
<i>Objectives:</i> Retinoic acid (RA) and benzoyl peroxide (BP) were studied, comparing their keratolytic efficacy and water barrier disruption to that of salicylic acid (SA), a well-established keratolytic, under similar conditions. <i>Patients/Methods:</i>Six volunteers were included in this blinded study.
J M, Waller, F, Dreher, S, Behnam, C, Ford, C, Lee, T, Tiet, G D, Weinstein, H I, Maibach   +7 more
openaire   +2 more sources

Direct Analysis of Salicylic Acid in Keratolytic Plaster by Gas–Solid Chromatography

Journal of Pharmaceutical Sciences, 1977
A rapid gas-solid chromatographic method is reported for the direct analysis of salicylic acid in keratolytic plaster. The method requires no preseparation or derivatization and takes about 14 min. Since it requires only 2-7 mg of sample, it can determine the salicylic acid concentration in a particular area of plaster.
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Keratolytic Treatment

2014
Ali Alikhan, Howard I. Maibach
openaire   +1 more source

Treatment of actinically damaged skin with a keratolytic gel.

Cutis, 1978
Rough-textured, actinically damaged skin of the extremities was treated with a keratolytic gel to restore the surface to a more normal appearance. The excellent improvement observed suggests that an abnormality of cell attachment may be the defect in some so-called dry skin states.
openaire   +1 more source