Results 131 to 140 of about 37,135 (247)
Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review
Photochemistry and Photobiology, EarlyView.Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto +5 morewiley +1 more sourceSafety and Efficacy of HexaBody‐DR5/DR5 in Malignant Solid Tumors: Phase 1/2a Results and Translational Insights Into Observed Hepatotoxicity
Clinical and Translational Science, Volume 19, Issue 6, June 2026.ABSTRACT
HexaBody‐DR5/DR5 (GEN1029) is a death receptor 5 (DR5) agonist composed of two humanized immunoglobulin G1 (IgG1) antibodies, Hx‐DR5‐01 and Hx‐DR5‐05, that bind non‐overlapping DR5 epitopes with nanomolar affinity. HexaBody‐DR5/DR5 is designed to activate the TRAIL pathway through DR5 clustering. This phase 1/2a, open‐label, multi‐center study Marije B. Overdijk, Kristin Strumane, Ruth Plummer, Patricia LoRusso, Jordi Rodon Ahnert, Udai Banerji, Elena Garralda, Emiliano Calvo, Han Si, Naomi Hoevenaars, Jens Thing Mortensen, Sieto Bosgra, Anders Malmberg, Merete Ellekilde‐Pedersen, Teresa Ramirez‐Andersen, Panagiota Diamantopoulou Reiter, Elena Favaro, Ulf Forssmann, Esther C. W. Breij, Maria Jure‐Kunkel +19 morewiley +1 more sourceTirbanibulin 1% real‐world use in 679 actinic keratoses patients during warm season (SUMM‐AK study)
Journal of the European Academy of Dermatology and Venereology, EarlyView.A. Carugno, G. Nazzaro, L. Argnani, F. Bellinato, E. Zappia, M. V. Masala, G. Dal Bello, M. Valenti, G. Addari, G. Ciccarese, M. Bruni, E. Trovato, G. Paolino, R. Balestri, A. D'Arino, C. Magnoni, E. Zavattaro, G. Toni, R. Giuffrida, A. Verdelli, S. Caccavale, A. Villani, S. Giacalone, S. Recalcati, S. Barruscotti, S. Bighetti, L. Bettolini, G. Fiorillo, L. Germi, S. Fazio, S. D. Infusino, L. Eibenschutz, A. Cesari, M. Dragotto, G. B. M. Zolo, P. Savoia, I. Zalaudek, E. Sala, E. Errichetti, S. R. Mercuri, M. Esposito, C. Foti, L. Atzori, M. Ardigò, P. Danese, S. Ribero, P. Gisondi, A. V. Marzano, N. Zerbinati +48 morewiley +1 more sourceThe Impact of Clinical and Dermoscopic Photographs on the Diagnostic Accuracy of Remote Optical Coherence Tomography Assessment for Basal Cell Carcinoma Detection: A Comparative Diagnostic Study
International Journal of Dermatology, Volume 65, Issue 6, Page 1231-1237, June 2026.ABSTRACT Background
Remote assessment of optical coherence tomography (OCT) scans for basal cell carcinoma (BCC) detection enhances access to OCT‐guided dermatologic care, but prohibits direct lesion inspection. The value of clinical and dermoscopic photographs when remotely assessing OCT scans remains unknown.Tom Wolswijk, Patricia Joan Nelemans, Frank van Leersum, Emmy Crüts, Myrthe Maria Gerarda Moermans, Lara Vreven, Lisa Maria Hillen, Klara Mosterd +7 morewiley +1 more sourcePhoto‐Controlled Antibacterial Drug Release From DASA‐Coated Silica Particles for Improved Treatment of Wound Infections
Advanced Functional Materials, Volume 36, Issue 38, 11 May 2026.Synthesis and characterization of light‐responsive donor–acceptor Stenhouse adducts (DASA)‐coated chlorhexidine‐loaded silica nanoparticles. Such a controllable drug‐delivery system enables the release of the antimicrobial drug on demand and in consecutive cycles, thereby maintaining the concentration within the therapeutic window.Michèle Clerc, Flavia Zuber, Lea Oberhänsli, Yvonne Elbs‐Glatz, Maria M. Miguel, Vera M. Kissling, Qun Ren, Markus Rottmar, Luciano F. Boesel, Giorgia Giovannini +9 morewiley +1 more sourceFabrication Technologies for Soft, Multimaterial Optical Fibers for In Vivo Diagnostics and Phototherapy, With a Focus on Extrusion Printing
Advanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.Soft multimaterial optical fibers integrate multiple functionalities—such as waveguiding, side emission, sensing, drug delivery or actuation—into a single filament for wearable, implantable, and tissue‐integrated devices for diagnostics and phototherapy.Zahra Kafrashian, Jun Feng, Aránzazu del Campo +2 morewiley +1 more sourceA Comprehensive Review of Traditional and Machine Learning‐Assisted Diffuse Optical Spectroscopy and Imaging Techniques for Dermatological Applications
Advanced Photonics Research, Volume 7, Issue 5, May 2026.This review critically examines clinical studies on both conventional and machine learning (ML)‐integrated diffuse optical spectroscopy and imaging methods for dermatological applications, with a primary focus on the past decade and inclusion of earlier foundational work where appropriate.Iftak Hussain, Li Xiuting, Randall Ang Jie, Keertana Vinod Ram, Mark Teo Ju Teng, Valerie Xinhui Teo, Malini Olivo, U. S. Dinish +7 morewiley +1 more source