Results 21 to 30 of about 50,520 (319)

A proposed scoring system for assessing the severity of actinic keratosis on the head: actinic keratosis area and severity index [PDF]

open access: yes, 2017
Background: Actinic keratosis (AK) severity is currently evaluated by subjective assessment of patients. Objectives: To develop and perform an initial pilot validation of a new easy-to-use quantitative tool for assessing AK severity on the head ...
Arkachaisri   +27 more
core   +1 more source

Randomized Trial of Four Treatment Approaches for Actinic Keratosis

open access: yesNew England Journal of Medicine, 2019
Background Actinic keratosis is the most frequent premalignant skin disease in the white population. In current guidelines, no clear recommendations are made about which treatment is preferred. Methods We investigated the effectiveness of four frequently
M. Jansen   +10 more
semanticscholar   +1 more source

A trial‐based cost‐effectiveness analysis of topical 5‐fluorouracil vs. imiquimod vs. ingenol mebutate vs. methyl aminolaevulinate conventional photodynamic therapy for the treatment of actinic keratosis in the head and neck area performed in the Netherlands

open access: yesBritish Journal of Dermatology, 2020
Actinic keratosis (AK) is a common premalignant skin condition that might have the ability to progress into squamous cell carcinoma. Due to the high incidence of AK, treatment of this disease significantly impacts healthcare spending.
M. Jansen   +6 more
semanticscholar   +1 more source

Clinical utility of ingenol mebutate in the management of actinic keratosis. Perspectives from clinical practice [PDF]

open access: yes, 2018
Actinic keratoses (AKs) are epidermal cutaneous neoplasia observed predominantly in middle-aged and older subjects with mainly photo type I and photo type II on sun-exposed surfaces as a result of DNA damage.
Bernardini, Nicoletta   +3 more
core   +1 more source

A review of actinic keratosis, skin field cancerisation and the efficacy of topical therapies

open access: yesAustralasian Journal of Dermatology, 2020
While a wide range of treatments exist for actinic keratosis and skin field cancerisation, the long‐term benefits of the most common topical therapies are poorly defined.
R. Sinclair   +4 more
semanticscholar   +1 more source

Prevalence and associated factors of skin cancer in aged nursing home residents: A multicenter prevalence study [PDF]

open access: yes, 2019
Non-melanoma-skin cancer is an emerging clinical problem in the elderly, fair skinned population which predominantly affects patients aged older than 70 years.
Akdeniz, Merve   +4 more
core   +1 more source

High‐frequency (20 MHz) high‐intensity focused ultrasound: New Treatment of actinic keratosis, basal cell carcinoma, and Kaposi sarcoma. An open‐label exploratory study

open access: yesSkin research and technology, 2020
Skin cancer is common, growing, challenging, and in need of progress in early‐stage treatment. 20 MHz high‐intensity focused ultrasound (HIFU) is new and applied to actinic keratosis (AK) and skin cancers for the first time.
J. Serup   +4 more
semanticscholar   +1 more source

Diagnostic Accuracy of Dermoscopy of Actinic Keratosis: A Systematic Review

open access: yesDermatology Practical & Conceptual, 2020
Introduction Dermoscopy is a tool that aids clinicians in the diagnosis of actinic keratosis; however, few diagnostic accuracy studies have determined its sensitivity and specificity for this diagnosis.
Karla L Valdés-Morales   +3 more
semanticscholar   +1 more source

Factors influencing response to ingenol mebutate therapy for actinic keratosis of face and scalp [PDF]

open access: yes, 2017
AIM To determine factors independently influencing response to ingenol mebutate therapy and assess efficacy on clinical setting of non-hypertrophic non-hyperkeratotic actinic keratosis (AK).
Balduzzi, Veronica   +9 more
core   +1 more source

The Suppressive Effect of Leucine-Rich Glioma Inactivated 3 (LGI3) Peptide on Impaired Skin Barrier Function in a Murine Model Atopic Dermatitis

open access: yesPharmaceutics, 2020
This study aimed to restore the skin barrier function from atopic dermatitis (AD) via treatment with leucine-rich glioma inactivated 3 (LGI3) peptide. Male NC/Nga mice (7 weeks, 20 g) were randomly allocated into three groups (control, AD, and LGI3 group)
Ui Seok Kim   +8 more
doaj   +1 more source

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