Results 241 to 250 of about 1,566,699 (318)

A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time

Advanced Science, EarlyView.
This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li, Qiang Ning, Zhen Li, Qian Zhang, Peilu Zhu, Jimin Zhan, Yunfu Li, Zhen Li, Liang Dong, Qing Xiong, Jiahao Liao, Jie Liu, David Jackson, Munenori Kitagawa, Zuxin Zhang, Lei Liu   +15 more
wiley   +1 more source

Lightweight Ultra‐Strength in AlFeNiTiV Complex Concentrated Alloys via Cu Microalloying‐Driven Lattice Coherency Tuning

Advanced Science, EarlyView.
This study develops a lightweight AlFeNiTiV complex concentrated alloy (density: 6.83 g cm−3) through Cu microalloying and lattice coherency tuning. The alloy exhibits ultrahigh compressive strength exceeding 3.3 GPa, 11.8% strain, and retains a yield strength of 1311.6 MPa at 600 °C, demonstrating a phase interface strategy for high‐temperature ...
Hongmei Chen, Weizong Bao, Jie Chen, Tao Hong, Bohua Yu, Xinxin Yang, Ning Ding, Jiayin Chen, Chaoran Wang, Zeyun Cai, Guoqiang Xie   +10 more
wiley   +1 more source

Comparison of Mask-R-CNN and Thresholding-Based Segmentation for High-Throughput Phenotyping of Walnut Kernel Color. [PDF]

Plants (Basel)
Lee SH, McDowell S, Leslie C, McCreery K, Earles M, Brown PJ.   +5 more
europepmc   +1 more source

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

Solving the QCD effective kinetic theory with neural networks. [PDF]

Eur Phys J C Part Fields
Cabodevila SB, Kurkela A, Lindenbauer F.
europepmc   +1 more source

Mechanism‐Driven Screening of Membrane‐Targeting and Pore‐Forming Antimicrobial Peptides

Advanced Science, EarlyView.
To combat antibiotic resistance, this study employs mechanism‐driven screening with machine learning to identify pore‐forming antimicrobial peptides from amphibian and human metaproteomes. Seven peptides are validated, showing minimal toxicity and membrane disruption.
Jiaxuan Li, Chenguang Yang, Ruihan Dong, Juan Francisco Bada Juarez, Lei Wang, Maximilian Emanuel Wettstein, Dali Wang, Chan Cao, Ying Lu, Chen Song   +9 more
wiley   +1 more source

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

Advanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou, Mingkun Lu, Zhimeng Zhou, Yanlin Ren, Xinyuan Yu, Ziqi Pan, Yuan Zhou, Hao Yang, Lingyan Zheng, Shukai Gu, Yang Zhang, Wei Hu, Fengcheng Li, Haibin Dai, Feng Zhu   +14 more
wiley   +1 more source

Comparative evaluation of emphysema quantification: Standardized %LAV-950 versus DL-based emphysema quantification with clinical parameter correlation. [PDF]

Medicine (Baltimore)
Belde D, Rakic J, Heimer J, Kettner M, Thali M, Euler A, Kubik-Huch RA, Niemann T.   +7 more
europepmc   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Advanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu   +14 more
wiley   +1 more source

Foliar application of selenium increased selenium accumulation, speciation, and bioaccessibility, as well as the yield and nutritional quality of sweet maize. [PDF]

Front Plant Sci
Asamoah EO, Ssemalawa SM, Danso OP, Wang Y, Farooq MR, Rao P, Sun H, Guo Y, Yin X, Chen Y.   +9 more
europepmc   +1 more source