Results 281 to 290 of about 1,278,153 (338)

Introducing the kernel descent optimizer for variational quantum algorithms. [PDF]

Sci Rep
Simon L, Eble H, Radons M.
europepmc   +1 more source

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

Advanced Science, EarlyView.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song, Zilv Mei, Qijie Zheng, Qingqing Yuan, Yu Liang, Jiaqi Gao, Lang Zhou, Shuheng Wu, Wei Wu   +8 more
wiley   +1 more source

Advanced deep learning approach for the fault severity classification of rolling-element bearings. [PDF]

Sci Rep
Parmar V, Layek S, Bhushan M, Mehta SS, Harsha SP, Sharma AK.   +5 more
europepmc   +1 more source

IPGCA: A Comprehensive Single Cell Atlas of 1 074 127 Porcine Intestinal Cells Revealing Cellular Dynamics, Genetic Regulation, and Cross‐Species Conservation

Advanced Science, EarlyView.
A high resolution integrated cell atlas of the pig intestine provides insights into the genetic mechanisms of complex traits (Created in BioRender. Yu, P. (2025) https://BioRender.com/o14c563) Abstract The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes.
Pengfei Yu, Qinqin Xie, Xiaodian Cai, Zhanming Zhong, Ran Wei, He Han, Shuang Liu, Zhenyang Zhang, Lingyao Xu, Zitao Chen, Zhe Zhang, Qishan Wang, Yuchun Pan, Zhen Wang, Zhe Zhang   +14 more
wiley   +1 more source

Fracture Behavior and Mechanisms of Wheat Kernels Under Mechanical Loading. [PDF]

Foods
Chen Y, Ma S, Wang X, Tian X.
europepmc   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Selection of heat stress tolerant wheat genotypes for desert environments. [PDF]

Sci Rep
Ghazy AI, Al Ateeq TK, Ibrahim EI, Abdel-Haleem H, Attia KA, Azab O, Al-Doss AA.   +6 more
europepmc   +1 more source

Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis

Advanced Science, EarlyView.
In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley   +1 more source

Using preprocessed datasets to construct and interpret multiclass identification models. [PDF]

Front Plant Sci
Wang C, Fu Y, Wan R, Zhao L, Wang H, Guo J, Liu Q, Li S, Ma S, Wang Z, Huang W, Liu H, Yang S, Nie C.   +13 more
europepmc   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source