Results 111 to 120 of about 114,264 (263)
Role of N-methyl-D-aspartate receptors in action-based predictive coding deficits in schizophrenia [PDF]
, 2017 Published in final edited form as:Biol Psychiatry. 2017 March 15; 81(6): 514–524. doi:10.1016/j.biopsych.2016.06.019.BACKGROUND: Recent theoretical models of schizophrenia posit that dysfunction of the neural mechanisms subserving predictive coding ...
Ford, Judith M. +7 more
core +1 more source
Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris
Advanced Science, EarlyView.A programmable colloidal microswarm is developed to quickly detach blood clots and enable rapid recanalization, with the detached debris functioning as a magnetic “debris‐robot” that can be efficiently propelled and retrieved via catheter suction, which could significantly save time compared to the critical “Golden 6 hours” window for ischemic stroke ...
Qinglong Wang +11 more
wiley +1 more source
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Erwin A. van Vliet +9 more
wiley +1 more source
Veterinární Medicína, 2018 In this study, we compared the effects of xylazine, medetomidine and dexmedetomidine in combination with ketamine on heart rate, respiratory rate, blood gas values, temperature and sedation scores. A total of 30 dogs were evaluated.
O. Guzel +5 more
doaj +1 more source
Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration
Advanced Science, EarlyView.This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong +17 more
wiley +1 more source
طب اورژانس ایران, 2016 Introduction: Nausea is a common side effect of ketamine in pediatric sedation and the controversy is still ongoing regarding use of anti-nausea drugs with ketamine to reduce this side effect.
Saeed Majidi Nejad +3 more
doaj
Structure and Dynamics of Brain Lobe's Functional Networks at the Onset of Anesthesia-Induced Loss of Consciousness [PDF]
arXiv, 2016 Anesthetic agents are neurotropic drugs capable of inducing significant alterations in the thalamocortical system, promoting a profound decrease in awareness and level of consciousness. There is experimental evidence that general anesthesia affects large-scale functional networks, leading to alterations in the brain's state.
arxiv
Ketamine for Pain in Sickle Cell Disease Reduces Opioid Usage [PDF]
CONTEXT: Pain attributable to sickle cell disease (SCD) is often unpredictable, recurrent, and requires complex treatments. Subanesthetic ketamine infusion has been studied in other diseases and disorders, but there is still limited data on its efficacy ...
Chumpitazi, Corrie E +6 more
core +2 more sources
A systematic review of therapeutic interventions to reduce acute and chronic post-surgical pain after amputation, thoracotomy or mastectomy [PDF]
, 2014 BACKGROUND: Perioperative neuropathic pain is under-recognized and often undertreated. Chronic pain may develop after any routine surgery, but it can have a far greater incidence after amputation, thoracotomy or mastectomy.
Ibarra M.M. +3 more
core +1 more source
Advanced Science, EarlyView.This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan +11 more
wiley +1 more source