Results 131 to 140 of about 196,719 (315)
A microscopically assisted limited colectomy mouse model of early colon cancer
Animal Models and Experimental Medicine, EarlyView.Establishment, surgery, and evaluation process of a microscope‐assisted limited colon resection mouse model for early‐stage colon cancer. Abstract Background Currently, there is a lack of an adequate rodent model for investigating surgical techniques and comprehensive treatment options for patients with colorectal cancer (CRC).
Yu Han +3 more
wiley +1 more source
Pharmacokinetics and Pharmacodynamics of Ketamine
The non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine offers a complex pharmacological profile which has led to its established role in anesthesia, analgesia, and psychiatry.
Saari, Teijo I. +3 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.DPSCs, hepatocytes, and exosomes were tested for liver fibrosis therapy. Exosome‐based treatment exhibited superior antioxidative and regenerative effects. Liver enzymes, oxidative stress, and profibrotic markers were significantly reduced. α‐SMA, desmin, and related gene expression were downregulated.
Sahar Rahimi +3 more
wiley +1 more source
MeCP2 prevents against sustained ketamine-induced synaptic depression at inhibitory synapses
iScienceSummary: Ketamine induces antidepressant action via upregulation of hippocampal brain-derived neurotrophic factor (BDNF) expression and TrkB receptor signaling.
Michelle K. Piazza +4 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes +3 more
wiley +1 more source
Frontiers in Veterinary ScienceTo evaluate the effects of increasing plasma ketamine concentration on isoflurane minimum alveolar concentration (MAC) in rabbits, six New Zealand white rabbits weighing 4.21 ± 0.35 kg were anesthetized with isoflurane in oxygen.
Linda S. Barter, Bruno H. Pypendop
doaj +1 more source
Ketamine Induced Seizures in an Autistic Child
, 2014 An autistic child of eight years age, with attention deficit hyperactivity syndrome presented for tooth extraction under general anaesthesia. Ketamine was used for induction and the child developed seizures following its administration.
Geetanjali S Verma, Prabhashankar
core
Arthritis &Rheumatology, EarlyView.Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla +13 more
wiley +1 more source
Use of a Ketamine-Propofol Combination During Sedation and Analgesia
, 2015 Aim: The aim of this study was to evaluate 1:1 mixture of ketamine and propofol for sedative/analgesic efficacy, patient comfort and postoperative complications.
Asım Esen +2 more
core +1 more source