Results 111 to 120 of about 196,719 (315)
Late Preconditioning is Blocked by Racemic Ketamine, But Not by S(+)-Ketamine
Anesthesia & Analgesia, 2001 Racemic ketamine blocks K(ATP) channels in isolated cells and abolishes short-term cardioprotection against prolonged ischemia. We investigated the effects of racemic ketamine and S(+)-ketamine on ischemic late preconditioning (LPC) in the rabbit heart in vivo. A coronary occluder was chronically implanted in 36 rabbits.
Müllenheim, J. +5 more
openaire +4 more sources
Case report: Treatment of burning pain and Post traumatic refractory Allodynia in foot digits, with low dose of ketamine [PDF]
Frequent simulation and irritation of NMDA receptors by glutamate mediators can lead to burning pain, allodynia and hyperalgesia, even after stopping the irritant factor.
ایمانی, فرناد +2 more
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Advanced Science, EarlyView.Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral +7 more
wiley +1 more source
Intranasal ketamine analgesia for non-physician prehospital clinicians
Prehospital analgesia is often under-administered within the UK for various reasons – especially within the paediatric population. Several analgesic options are available in the ambulance service with ketamine being a versatile medication often used by ...
Pawley, Steve, Worthington, Judith
core +1 more source
Repeated exposure to ketamine in adolescent rats results in persistent anxiety in the adulthood [PDF]
, 2018 Adolescent development of the prefrontal cortex (PFC) is accompanied by important changes in glutamatergic, GABAergic and dopaminergic circuitries, susceptible to modulation by N-methyl-D-aspartate receptors (NMDAR) antagonists.
Summavielle, Teresa +6 more
core +1 more source
Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Advanced Science, EarlyView.Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
Unique Effects of (R)-Ketamine Compared to (S)-Ketamine on EEG Theta Power in Rats
PharmaceuticalsDifferences in the pharmacological effects of (S)-ketamine and (R)-ketamine are at the focus of research. Clinical data and our rat studies confirmed the antidepressant effect of (S)- but not (R)-ketamine, with similar differences in quantitative ...
Dóra Pothorszki +4 more
doaj +1 more source
, 1996 Twenty grey duiker (Sylvicapra grimmia) were blow-darted with a combination of ketamine and xylazine, resulting in a level of sedation adequate for capture and minor procedures in 13 of them (mean dosages: ketamine, 13.4 mg/kg; xylazine, 16.8 mg/kg ...
Wilson, K. +3 more
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Advanced Science, EarlyView.This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun +14 more
wiley +1 more source