Results 131 to 140 of about 114,264 (263)
Comparison of the analgesic effect of intra-articular and extra-articular injection of morphine and ketamine compound in arthrotomy lower limb surgery under spinal anesthesia [PDF]
, 1969 Reza Akhondzade +4 more
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Advanced Science, EarlyView.This study develops an Au/S‐doped reduced graphene oxide (Au@S‐rGO) sensor for rapid fentanyl detection. DFT simulations and structural analysis confirm atomically dispersed Au/S configurations, enhancing catalytic activity. The sensor achieves a 9.7 nmol L−1 detection limit, 98–104% recovery in human serum, and 85.7–93.6% consistency with mass ...
Meng Li +9 more
wiley +1 more source
Glia, Volume 71, Issue 2, Page 334-349, February 2023., 2023 Main Points Defined a pig microglial transcriptome signature comprising 239 genes. Demonstrated regional variance in the pig microglial transcriptome across the brain. Revealed similarity of pig microglial gene expression to that of human and mouse microglia.
Barbara B. Shih +8 more
wiley +1 more source
Ketamine induces apoptosis in lung adenocarcinoma cells by regulating the expression of CD69
Cancer Medicine, 2018 Ketamine, an anesthetic, analgesic, or sedative, is widely used for the treatment of cancer pain. Recently, ketamine has been also reported to be tumor repressor for inhibiting proliferation, invasion, and migration, and inducing apoptosis in many ...
Xuhui Zhou +6 more
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Circulatory Responses to Ketamine Anesthesia [PDF]
, 1972 W. A. Tweed, M. Minuck, David Mymin
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Advanced Science, EarlyView.Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang +8 more
wiley +1 more source
Neurobiology of Disease, 2012 Ketamine is an NMDA receptor antagonist with psychotomimetic, dissociative, amnestic and euphoric effects. When chronically abused, ketamine users display deficits in cognition and information processing, even following long-term abstinence from the drug.
Robert E. Featherstone +5 more
doaj
Two-Layer Retrieval-Augmented Generation Framework for Low-Resource Medical Question Answering Using Reddit Data: Proof-of-Concept Study [PDF]
The increasing use of social media to share lived and living experiences of substance use presents a unique opportunity to obtain information on side effects, use patterns, and opinions on novel psychoactive substances. However, due to the large volume of data, obtaining useful insights through natural language processing technologies such as large ...
arxiv +1 more source
Advanced Science, EarlyView.The aldehyde‐ and catechol‐modified starch (ACS) microparticle (MP) is developed by chemical modifications and freeze‐milling after calcium intercalation for highly absorbent and tissue‐adhesive properties. The ACS‐MP can be self‐gelled upon contact with biological fluids and blood on tissue surfaces, rapidly absorbing them and achieving robust wet ...
Soohwan An +7 more
wiley +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source