Results 131 to 140 of about 345,134 (373)
Neurobiology of Disease, 2012 Ketamine is an NMDA receptor antagonist with psychotomimetic, dissociative, amnestic and euphoric effects. When chronically abused, ketamine users display deficits in cognition and information processing, even following long-term abstinence from the drug.
Robert E. Featherstone +5 more
doaj +1 more source
Advanced Science, EarlyView.We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu +7 more
wiley +1 more source
An index of fatal toxicity for new psychoactive substances [PDF]
, 2018 The final, definitive version of this paper has been published in Journal of Psychopharmacology, February 2018, published by SAGE Publishing, All rights reserved.An index of fatal toxicity for new psychoactive substances has been developed based solely ...
Corkery, John, King, L.A.
core +2 more sources
Regional anesthesia and pain medicine, 2018 Background Over the past 2 decades, the use of intravenous ketamine infusions as a treatment for chronic pain has increased dramatically, with wide variation in patient selection, dosing, and monitoring.
Steven P. Cohen +11 more
semanticscholar +1 more source
Advanced Science, EarlyView.The present study investigates a cone‐specific STX3 knockout model, displaying a complete loss of cone function, a later onset reduction in rod function, and photoreceptor cell death. A cone‐specific depletion of STXBP1 and ARR4 could be observed in this model.
Lars Tebbe +5 more
wiley +1 more source
Perioperative intravenous ketamine for acute postoperative pain in adults.
Cochrane Database of Systematic Reviews, 2018 BACKGROUND Inadequate pain management after surgery increases the risk of postoperative complications and may predispose for chronic postsurgical pain.
E. Brinck +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.A super‐conductive ionic patch reprograms the post‐infarction microenvironment by enabling stable ionic migration and electrical signal transmission within damaged myocardium. The patch rapidly adheres to cardiac tissue, enhances conduction velocity, suppresses excitation‐contraction decoupling, and promotes structural and functional cardiac repair in ...
Changyong Wang +8 more
wiley +1 more source
Ketamine induces apoptosis in lung adenocarcinoma cells by regulating the expression of CD69
Cancer Medicine, 2018 Ketamine, an anesthetic, analgesic, or sedative, is widely used for the treatment of cancer pain. Recently, ketamine has been also reported to be tumor repressor for inhibiting proliferation, invasion, and migration, and inducing apoptosis in many ...
Xuhui Zhou +6 more
doaj +1 more source
Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans
Advanced Science, EarlyView.This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang +17 more
wiley +1 more source