Results 151 to 160 of about 345,134 (373)

Attenuation of Antidepressant Effects of Ketamine by Opioid Receptor Antagonism.

American Journal of Psychiatry, 2018
OBJECTIVE: In addition to N-methyl-d-aspartate receptor antagonism, ketamine produces opioid system activation. The objective of this study was to determine whether opioid receptor antagonism prior to administration of intravenous ketamine attenuates its
N. Williams, Boris D Heifets, C. Blasey, K. Sudheimer, J. Pannu, Heather Pankow, J. Hawkins, J. Birnbaum, D. M. Lyons, C. Rodriguez, A. Schatzberg   +10 more
semanticscholar   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Ketamine-Aminophylline induced Decrease in Soizure Threshold [PDF]

, 1982
Carol A. Hirshman, Walter Krieger, Gail Littlejohn, Rodney Lee, R. Julien   +4 more
openalex   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis

Hepatology, EarlyView., 2022
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree   +19 more
wiley   +1 more source

Arbitrary 3D Organic Mixed Ionic‐Electronic Conductor Architectures via Self‐Fusion of PEDOT:PSS Microfibers

Advanced Science, EarlyView.
A general fabricating strategy for arbitrary 3D organic mixed ionic‐electronic conductor architectures is reported using PEDOT:PSS microfiber building blocks. A water‐assisted self‐fusion process is successfully developed in which adhesion can be modulated as reversible (PSS‐rich) or irreversible (PEDOT‐rich) self‐fusion depending on the post‐treatment
Youngseok Kim, Jongwon Lee, Jiwoong Kim, Jung Il Yoo, Junggeon Park, Jaeyoung Lee, Heung Cho Ko, HyungJu Ahn, Myung‐Han Yoon   +8 more
wiley   +1 more source

Comparison of nebulized dexmedetomidine and ketamine for premedication in pediatric patients undergoing hernia repair surgery: a randomized comparative trial [PDF]

, 2022
Geeta Singariya, Namita Malhotra, Manoj Kamal, Rishabh Jaju, Shruti Aggarwal, Pooja Bihani   +5 more
openalex   +1 more source

The Effect of Ketamine on Posttonsillectomy Pain in Children: A Clinical Trial [PDF]

Introduction: Tonsillectomy is one of the most common surgical operations and has such complications as pain, hemorrhage and laryngospasm. Pain management is of vital importance in order to reduce the suffering and restlessness in children having ...
انتظاری, مسعود, علاف اکبری, سوره, محمدی, محمدعلی, پیرزاده, اکبر   +3 more
core  

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Role of Low dose Ketamine (0.05 and 0.1 mg/kg) in Alleviating Propofol Injection Pain

, 2022
Amal Hilal Sulaiman Al Mamari, Abdullah Al Jadidi, Rashid M. Khan, Naresh Kumar Kaul   +3 more
openalex   +1 more source