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Progress in the Application and Scheme of the Ketogenic Diet in the Treatment of Metabolic Diseases
Ketogenic diets have been shown to play a role in some metabolic diseases and neurodegenerative diseases as a low-carbohydrate, high-fat diets supplemented with appropriate protein. Ketogenic diets have been proven effective, but the mechanisms of action
Yuqi LI +5 more
doaj +1 more source
About one third of patients with epilepsy are pharmacoresistent. For a subgroup of this population, the ketogenic diet can be highly efficacious and should be considered early. This review discusses the different types of ketogenic diet, proposed mechanism of actions and its evidence for use in children and adults with both generalized and focal ...
Radhika, Dhamija +2 more
openaire +2 more sources
ATP-gated potassium channels contribute to ketogenic diet-mediated analgesia in mice
Chronic pain is a substantial health burden and options for treating chronic pain remain minimally effective. Ketogenic diets are emerging as well-tolerated, effective therapeutic strategies in preclinical models of chronic pain, especially diabetic ...
Jonathan D. Enders +7 more
doaj +1 more source
Therapeutic effect of ketogenic diet treatment on type 2 diabetes
Diet plays an important role in diabetes development. The effect of ketogenic diet on type 2 diabetes remains elusive. In this study, we collect diabetes related physiological parameters and abdominal MRI images to evaluate the effect of ketogenic diet ...
Fang Li +11 more
doaj +1 more source
The Neuropharmacology of the Ketogenic Diet [PDF]
The ketogenic diet is a valuable therapeutic approach for epilepsy, one in which most clinical experience has been with children. Although the mechanism by which the diet protects against seizures is unknown, there is evidence that it causes effects on intermediary metabolism that influence the dynamics of the major inhibitory and excitatory ...
Adam L, Hartman +3 more
openaire +2 more sources
Objective:Patients with intractable childhood epilepsy may benefit from ketogenic diet treatment. Management of ketogenic diet depends on the knowledge level and practice and attitudes of their caregivers.
Sinem Bayram, Hilal Çalışkan
doaj +1 more source
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy [PDF]
Background: Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect.
Stefan Walenta +26 more
core +2 more sources
Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet. [PDF]
The ketogenic diet is a high-fat, low-carbohydrate regimen that forces ketone-based rather than glucose-based cellular metabolism. Clinically, maintenance on a ketogenic diet has been proven effective in treating pediatric epilepsy and type II diabetes ...
David N Ruskin +2 more
doaj +1 more source
Ketogenic diets, not for everyone
The adoption of low-carbohydrate diets can lead to weight loss in many patients. However, these now widespread diets also have the potential to exacerbate hypercholesterolemia.The objective of this study is to display the potentially harmful effects of the ketogenic diet on cholesterol levels in patients with or without underlying hyperlipidemia.We ...
Ira J. Goldberg +7 more
openaire +3 more sources
Lowering dietary carbohydrates to manage obesity and related disease: A systematic review and theoretical framework [PDF]
This study aimed to evaluate the lowering of carbohydrates from conventionally recommended levels of ->55% of energy intake as a valid and safe treatment option for managing obesity and related disease.
Verma, Radhika
core +2 more sources

