Results 41 to 50 of about 25,226 (299)

Impact of ketogenic diets on cancer patient outcomes: a systematic review and meta-analysis

open access: yesFrontiers in Nutrition
BackgroundThe ketogenic diet, characterized by high fat, moderate protein, and extremely low carbohydrate intake, has been widely used as a medical treatment for various conditions and has gained increasing attention in recent years due to its health ...
Meiying Zhang   +4 more
doaj   +1 more source

Ketogenic diet improves core symptoms of autism in BTBR mice. [PDF]

open access: yesPLoS ONE, 2013
Autism spectrum disorders share three core symptoms: impaired sociability, repetitive behaviors and communication deficits. Incidence is rising, and current treatments are inadequate.
David N Ruskin   +7 more
doaj   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

The Effects Of Ketogenic Diet On Chronic Stress

open access: yes, 2023
Ketogenic diet, a high-fat and low-carbohydrate diet, is a nutritional therapeutic fasting diet that alters the body’s metabolism from glycolysis to fatty acid utilisation.
Ann-Katrin Kraeuter
core   +1 more source

The ketogenic diet and other dietary treatments for refractory epilepsy in children

open access: yesAnnals of Indian Academy of Neurology, 2014
The ketogenic diet is a high-fat, low-carbohydrate, and restricted protein diet that is useful in patients with refractory epilepsy. The efficacy of the ketogenic diet is better than most of the new antiepileptic drugs.
Suvasini Sharma, Puneet Jain
doaj   +1 more source

Enhanced Glycolysis‐Driven Histone H3K18 Lactylation Regulates Epileptogenesis by Modulating the E3 Ubiquitin Ligase COP1

open access: yesAdvanced Science, EarlyView.
Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng   +8 more
wiley   +1 more source

Isoenergetic feeding of low carbohydrate-high fat diets does not increase brown adipose tissue thermogenic capacity in rats [PDF]

open access: yes, 2012
Low-carbohydrate, high-fat (LC-HF) diets are popular for inducing weight loss in overweighed adults. Adaptive thermogenesis increased by specific effects of macronutrients on energy expenditure has been postulated to induce this weight loss.
Bidlingmaier, Martin   +54 more
core   +1 more source

Practical guidelines for addressing common questions and misconceptions about the ketogenic diet

open access: yesJournal of Metabolic Health
Research publications on the ketogenic diet have experienced an exponential increase in recent years, driving clinical interest, which has expanded along with media interest.
Sarah M. Rice, Douglas B. Reynolds
doaj   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

open access: yesAdvanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak   +9 more
wiley   +1 more source

Lowering dietary carbohydrates to manage obesity and related disease: A systematic review and theoretical framework [PDF]

open access: yes, 2012
This study aimed to evaluate the lowering of carbohydrates from conventionally recommended levels of ->55% of energy intake as a valid and safe treatment option for managing obesity and related disease.
Verma, Radhika
core  

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