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Multidrug-resistant Streptococcus pneumoniae infections: current and future therapeutic options.
, 2007 Antibacterial resistance in Streptococcus pneumoniae is increasing worldwide, affecting principally beta-lactams and macrolides (prevalence ranging between approximately 1% and 90% depending on the geographical area).
Peetermans, Willy E. +7 more
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Biosynthetic Origin of the Ether Ring in Platensimycin
, 2016 Platensimycin (PTM) and platencin (PTN) are highly functionalized bacterial diterpenoid natural products that target bacterial and mammalian fatty acid synthases. PTM and PTN feature varying diterpene-derived ketolides that are linked to the same 3-amino-
Jeffrey D. Rudolf (1328910) +3 more
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, 2013 The model is structured according to age and antibiotic exposure: 3 age groups (15 years) and 4 types of exposure (none, penicillin, macrolides, ketolides). (A) For each age/antibiotic exposure combination, 3 possible carriage (C) statuses are described:
Didier Guillemot (69521) +6 more
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Corrigendum to “Application of PK/PD Modeling in Veterinary Field: Dose Optimization and Drug Resistance Prediction” [PDF]
, 2016 International audienceIn the article titled “Application of PK/PD Modeling in Veterinary Field: Dose Optimization and Drug Resistance Prediction” [1], there was an error in Table .
Ahmad, Ijaz +9 more
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, 2013 The continuing increase in antibiotic-resistant microorganisms is driving the search for new antibiotic targets and improved antimicrobial agents. Ketolides are semisynthetic derivatives of macrolide antibiotics, which are effective against certain ...
Rodgers, Ward +2 more
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, 1998 The fourth International Conference on the Macrolides, Azalides, Streptogramins & Ketolides.
L. MINOLI +5 more
core
Erythromycin-induced insensitivity of coagulase-negative staphylococci to telithromycin
Current Issues in Pharmacy and Medical SciencesTelithromycin represents a new group of antibiotics, called ketolides, belonging to the same family as MLSB (macrolide, lincosamide, streptogramin B) antibiotics.
Marek Juda +5 more
doaj
Preferential Inhibition of Protein Synthesis by Ketolide Antibiotics in Haemophilus Influenzae Cells
, 2003 The ketolide antibiotics are semi-synthetic derivatives of erythromycin A with enhanced inhibitory activity in a wide variety of microorganisms. They have significantly lower MICs than the macrolide antibiotics for many Gram-positive organisms.
Tober, Craig L., Champney, W. Scott
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, 2009 isolates each of Chlamydia trachomatis and Chlamydia (Chlamydophila) pneumoniae were tested. The MIC at which 90 % of the isolates of both C. trachomatis and C.
Charles Parker +3 more
core
Impact of ketolide prescriptions on the emergence and selection of multiresistant S. pneumoniae.
, 2013 Evolutions of multiresistant-strain carriage as a function of time are shown. These simulations were carried out according to the 2 scenarios of K prescriptions: (A) K-Adults: ketolides were only used by adults after 2007, with 4 different replacement ...
Didier Guillemot (69521) +6 more
core +1 more source