Results 131 to 140 of about 1,365 (197)

Six-Year Prescription Pattern of Antimicrobial Use in Cats at the Veterinary Teaching Hospital of the University of Pisa. [PDF]

Animals (Basel)
De Marchi L, Vernaccini M, Meucci V, Briganti A, Lippi I, Marchetti V, Intorre L.   +6 more
europepmc   +1 more source

Molecular typing and antimicrobial susceptibility profiles of Campylobacter jejuni and Campylobacter coli Isolates from Patients and raw meat in Huzhou, China, 2021-2022. [PDF]

PLoS One
Wu X, Liping C, Dong F, Yan W, Shen Y, Ji L.   +5 more
europepmc   +1 more source

Addressing urgent priorities in antibiotic development: insights from WHO 2023 antibacterial clinical pipeline analyses.

Lancet Microbe
Melchiorri D, Rocke T, Alm RA, Cameron AM, Gigante V.   +4 more
europepmc   +1 more source

<i>In vitro</i> antimicrobial susceptibility of <i>Mycoplasma pneumoniae</i> isolates across different regions of China in 2023. [PDF]

JAC Antimicrob Resist
Yan C, Chen Y, Ren X, Jia X, Du B, Zhao H, Feng Y, Xue G, Cui J, Liu X, Yuan J.   +10 more
europepmc   +1 more source

Designing the Next Generation of Antibiotics: Structure, SAR, and Strategy in Medicinal Chemistry (2000-2025). [PDF]

Med Res Rev
Al-Karmalawy AA, Al-Dakhil A, Ashour NA, Yousef TA, Mabrouk SS, Khatib AOA, Hawas SS.   +6 more
europepmc   +1 more source

Resistance to macrolides-lincosamides-streptogramins and ketolides in staphylococci and streptococci, and new therapeutic strategies.

, 2000
Moreillon, P.
core   +1 more source

Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2015
Ketolides are promising new antimicrobials effective against a broad range of Gram-positive pathogens, in part because of the low propensity of these drugs to trigger the expression of resistance genes.
Stephen Douthwaite, David H. Sherman, Alexander S Mankin   +2 more
exaly   +9 more sources

Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site

Journal of Antimicrobial Chemotherapy, 2001
Ketolides are the most recent generation of antimicrobials derived from the 14-membered ring macrolide, erythromycin A. The main structural feature that differentiates ketolides from erythromycin is the keto group, which replaces the L-cladinose moiety ...
Stephen Douthwaite, W Scott Champney, W S Champney   +2 more
exaly   +2 more sources

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The Ketolides

Drugs, 2002
Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides are semi-synthetic derivatives of the 14-membered macrolide erythromycin A, and retain the erythromycin macrolactone ring structure as well as the D-desosamine sugar attached at position 5.
George G, Zhanel, Michael, Walters, Ayman, Noreddin, Lavern M, Vercaigne, Aleksandra, Wierzbowski, John M, Embil, Alfred S, Gin, Stephen, Douthwaite, Daryl J, Hoban   +8 more
openaire   +4 more sources

Telithromycin: The First of the Ketolides

Annals of Pharmacotherapy, 2002
OBJECTIVE: To review the chemistry, spectrum of activity, pharmacology, clinical efficacy, and safety of telithromycin. DATA SOURCES: A MEDLINE search from 1966 to December 2000 was performed via OVID and PubMed using the following ...
Christopher S, Shain, Guy W, Amsden
openaire   +2 more sources