Results 161 to 170 of about 1,365 (197)

[Telithromycin, first ketolide].

Revue medicale de Bruxelles, 2003
Telithromycine is the first ketolide on the market. Its characteristics are the two sites fixation on the bacterial ribosomia and and as a consequence a good activity on the majority of penicillin and macrolides resistant bacteria, included S. pneumonia and S. pyogenes.
Y, Van Laethem, J, Sternon
openaire   +1 more source

Macrolide and Ketolide Resistance with Streptococcus pneumoniae

Medical Clinics of North America, 2006
Antimicrobial agents in the macrolide family have long been considered drugs of potential utility in the management of infections caused by Streptococcus pneumoniae. However, with the emergence of macrolide resistance, the clinical value of macrolides in pneumococcal infections is threatened.
openaire   +2 more sources

Macrolides, Azalides, and Ketolides

2011
The macrolides and azalides are a generally well-tolerated class of antimicrobials used to treat several mild-to-moderate infections associated with Gram-positive microorganism. Over 50 years of clinical experience with the macrolides has also led to the observation of non-antimicrobial properties that are now being exploited in clinical practice.
openaire   +1 more source

[Macrolides, ketolides and streptogramins].

Enfermedades infecciosas y microbiologia clinica, 2003
Macrolides, ketolides and streptogramins are three families of antibiotics with different chemical structures, sharing the same mechanism of action. All three bind to distinct bases of the peptidyl transferase center of ARNr 23S. Their antibacterial spectrum practically overlaps, but dissimilarities in affinity and/or number of binding sites determine ...
José, Mensa, Elisa, García-Vázquez, Jordi, Vila   +2 more
openaire   +1 more source

Macrolide, Azalide, and Ketolides

2007
Sanjay Jain, William Bishai, Charles H. Nightingale   +2 more
openaire   +2 more sources

A journey across the sequential development of macrolides and ketolides related to erythromycin

Tetrahedron, 2006
Sarbani Pal
exaly  

New research in macrolides and ketolides since 1997

Expert Opinion on Investigational Drugs, 1999
André Bryskier, A Bryskier
exaly  

Ketolides

2006
openaire   +1 more source

Synthesis and antibacterial activity of novel ketolides with 11,12-quinoylalkyl side chains

Bioorganic and Medicinal Chemistry Letters, 2018
Zhe-Hui Zhao
exaly  

Ketolides

2014
openaire   +1 more source