Results 91 to 100 of about 1,080 (156)
Six-Year Prescription Pattern of Antimicrobial Use in Cats at the Veterinary Teaching Hospital of the University of Pisa. [PDF]
De Marchi L +6 more
europepmc +1 more source
Prevalence, antibiotic resistance, resistance and virulence determinants of Campylobacter jejuni in China: A systematic review and meta-analysis. [PDF]
Li Z +8 more
europepmc +1 more source
The Paradox of Healthcare in the 'Superbugs' Era: Current Challenges and Future Directions. [PDF]
Sole E +7 more
europepmc +1 more source
Postoperative Empyema Due to Leclercia adecarboxylata Following Mesothelioma Surgery: A Case Report. [PDF]
Montenegro JF +6 more
europepmc +1 more source
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Drugs, 2002
Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides are semi-synthetic derivatives of the 14-membered macrolide erythromycin A, and retain the erythromycin macrolactone ring structure as well as the D-desosamine sugar attached at position 5.
George G, Zhanel +8 more
openaire +4 more sources
Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides are semi-synthetic derivatives of the 14-membered macrolide erythromycin A, and retain the erythromycin macrolactone ring structure as well as the D-desosamine sugar attached at position 5.
George G, Zhanel +8 more
openaire +4 more sources
Telithromycin: The First of the Ketolides
Annals of Pharmacotherapy, 2002OBJECTIVE: To review the chemistry, spectrum of activity, pharmacology, clinical efficacy, and safety of telithromycin. DATA SOURCES: A MEDLINE search from 1966 to December 2000 was performed via OVID and PubMed using the following ...
Christopher S, Shain, Guy W, Amsden
openaire +2 more sources
A novel bicyclic ketolide derivative
Bioorganic & Medicinal Chemistry Letters, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Ying, Zhao, Qidong, You, Wenbin, Shen
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Enfermedades infecciosas y microbiologia clinica, 2010
Macrolides and ketolides are two families of antibiotics that share the same mechanism of action. They bind to different bases of the peptidyl transferase center of 23S RNA. The antibacterial spectrum of these drugs virtually overlaps, but dissimilarities in the affinity and number of binding sites results in differences in the intensity of their ...
Nazaret, Cobos-Trigueros +3 more
openaire +3 more sources
Macrolides and ketolides are two families of antibiotics that share the same mechanism of action. They bind to different bases of the peptidyl transferase center of 23S RNA. The antibacterial spectrum of these drugs virtually overlaps, but dissimilarities in the affinity and number of binding sites results in differences in the intensity of their ...
Nazaret, Cobos-Trigueros +3 more
openaire +3 more sources
Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides [PDF]
Significance Studies of antibiotic resistance are usually initiated in earnest only after resistance has become established in clinical pathogens. Here, we forewarn of a resistance mechanism to the novel antibiotics ketolides, which are only coming into broad medical practice.
Stephen Douthwaite +2 more
exaly +4 more sources

