Results 91 to 100 of about 1,080 (156)

Six-Year Prescription Pattern of Antimicrobial Use in Cats at the Veterinary Teaching Hospital of the University of Pisa. [PDF]

open access: yesAnimals (Basel)
De Marchi L   +6 more
europepmc   +1 more source

The Paradox of Healthcare in the 'Superbugs' Era: Current Challenges and Future Directions. [PDF]

open access: yesPathogens
Sole E   +7 more
europepmc   +1 more source

Postoperative Empyema Due to Leclercia adecarboxylata Following Mesothelioma Surgery: A Case Report. [PDF]

open access: yesPathogens
Montenegro JF   +6 more
europepmc   +1 more source
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The Ketolides

Drugs, 2002
Ketolides are a new class of macrolides designed particularly to combat respiratory tract pathogens that have acquired resistance to macrolides. The ketolides are semi-synthetic derivatives of the 14-membered macrolide erythromycin A, and retain the erythromycin macrolactone ring structure as well as the D-desosamine sugar attached at position 5.
George G, Zhanel   +8 more
openaire   +4 more sources

Telithromycin: The First of the Ketolides

Annals of Pharmacotherapy, 2002
OBJECTIVE: To review the chemistry, spectrum of activity, pharmacology, clinical efficacy, and safety of telithromycin. DATA SOURCES: A MEDLINE search from 1966 to December 2000 was performed via OVID and PubMed using the following ...
Christopher S, Shain, Guy W, Amsden
openaire   +2 more sources

A novel bicyclic ketolide derivative

Bioorganic & Medicinal Chemistry Letters, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ying, Zhao, Qidong, You, Wenbin, Shen
openaire   +2 more sources

[Macrolides and ketolides].

Enfermedades infecciosas y microbiologia clinica, 2010
Macrolides and ketolides are two families of antibiotics that share the same mechanism of action. They bind to different bases of the peptidyl transferase center of 23S RNA. The antibacterial spectrum of these drugs virtually overlaps, but dissimilarities in the affinity and number of binding sites results in differences in the intensity of their ...
Nazaret, Cobos-Trigueros   +3 more
openaire   +3 more sources

Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Significance Studies of antibiotic resistance are usually initiated in earnest only after resistance has become established in clinical pathogens. Here, we forewarn of a resistance mechanism to the novel antibiotics ketolides, which are only coming into broad medical practice.
Stephen Douthwaite   +2 more
exaly   +4 more sources

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