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Macrolides, Azalides, and Ketolides
2011The macrolides and azalides are a generally well-tolerated class of antimicrobials used to treat several mild-to-moderate infections associated with Gram-positive microorganism. Over 50 years of clinical experience with the macrolides has also led to the observation of non-antimicrobial properties that are now being exploited in clinical practice.
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Macrolides and ketolides: azithromycin, clarithromycin, telithromycin
Infectious Disease Clinics of North America, 2004The advanced macrolides, azithromycin and clarithromycin, and the ketolide telithromycin are structural analogues of erythromycin. They have several distinct advantages when compared with erythromycin including enhanced spectrum of activity, more favorable pharmacokinetics and pharmacodynamics, once daily administration, and improved tolerability. This
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Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides
Bioorganic and Medicinal Chemistry Letters, 2004Angela M Nilius +2 more
exaly +2 more sources
A journey across the sequential development of macrolides and ketolides related to erythromycin
Tetrahedron, 2006Sarbani Pal
exaly
New research in macrolides and ketolides since 1997
Expert Opinion on Investigational Drugs, 1999A Bryskier
exaly
Structural Basis for the Antibiotic Activity of Ketolides and Azalides
Structure, 2003Raz Zarivach, François Franceschi
exaly