Results 221 to 230 of about 455,246 (392)

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

Advanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu, Shumin Li, Jiaji Wu, Shumin Xu, Mo Shen, Chenyang Wang, Lundqvist Andreas, Jianghao Yu, Zhiyong Xu, Yueli Shi, Nana Liu, Yunke Yang, Jiangnan Zhao, Ying Yang, Pingli Wang, Peng Yi, Jin Cheng, Junhui Sun, Mengshu Li, Peng Xiao, Kai Wang   +20 more
wiley   +1 more source

Untersuchungen über Ketone der aromatischen Reihe:Benzophenon [PDF]

, 1878
Wilhelm Städel
openalex   +1 more source

MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells

Advanced Science, EarlyView.
This study demonstrates that the transport of lactate to the mitochondria is of critical importance in determining the functions of macrophages by altering mitochondrial respiration. In macrophages, this lactate transport mechanism regulates glucose homeostasis by influencing the functions of insulin‐secreting cells in the pancreatic islets.
Lingling Chen, Yijun Lin, Xinyu Zhu, Shixuan Zhuo, Zixuan Li, Cheng Guo, Xiaoyi Ye, Jinzhu Chen, Shuying Wang, Yan Chen   +9 more
wiley   +1 more source

Ketone drink enhances therapeutic efficacy in prostate cancer by targeting EZH2. [PDF]

Oncogenesis
Yum C, Schaefer RA, Wang R, Wang TY, Lu X, Liu Q, Ren Y, Meng Q, Yang Y, Zhang X, Xiong Y, Yu X, Zhang X, Jin J, Dong X, Yi Y, Yang R, Cao Q.   +17 more
europepmc   +1 more source

Über eine neue Methode zur Darstellung cyclischer Ketone I [PDF]

, 1914
Alfred Schaarschmidt
openalex   +1 more source

Split‐Aperture Xolography – Linear Volumetric Photoactivation with Short Axial Dimension and Low out of Focus Excitation

Advanced Science, EarlyView.
Stepwise excitation of dual‐color responsive molecules in a novel intersecting half‐cone geometry provides excellent spatial resolution while retaining the high efficiency and thus speed of the overall process. The approach provides volumetric methods with an enhanced performance at the nanoscale.
Martin Regehly, Stefan Hecht
wiley   +1 more source

Search for common genetic variants to allow reliable Mendelian randomization investigations into ketone metabolism. [PDF]

Eur J Epidemiol
Jiesisibieke ZL, Cronjé HT, Schooling CM, Burgess S.   +3 more
europepmc   +1 more source

Ueber die Einwirkung von Malonsäureester auf ungesättigte Ketone [PDF]

, 1899
D. Vorländer, Stefanie Gärtner
openalex   +1 more source

Natural Toolbox–Chemical Engineering Aspect and High‐Value Applications of Janus Cellulose Nanomaterials

Advanced Science, Volume 12, Issue 28, July 24, 2025.
The Tai Ji symbol from China represents the co‐existence of two opposite substances, similar to quantum entanglement. The term Janus comes from ancient Roman religion and mythology. Janus, the god of beginnings, transitions, etc., has two faces, symbolizing duality. Janus cellulose nanomaterials show structural duality.
Yu Zhao, Shengjie Wang, Zongchen Wei, Shiming Qiu, Guofu Zhou, Jr‐Hau He, Xuezhu Xu   +6 more
wiley   +1 more source

The origin of hydroxy-cyclohexenone fatty acids from skin barrier protein and relevance to covalent binding of ceramides. [PDF]

J Lipid Res
Noguchi S, Boeglin WE, Nakashima F, Stec DF, Calcutt MW, Takeichi T, Akiyama M, Brash AR.   +7 more
europepmc   +1 more source