Results 281 to 290 of about 331,332 (337)

Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection

open access: yesAngewandte Chemie, EarlyView.
In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González   +5 more
wiley   +1 more source

Pyridine Into Pyrrole Transformation Induced Within the Confinement of the Macrocycle

open access: yesAngewandte Chemie, EarlyView.
This work demonstrates the nontrivial reactivity of pyridine incorporated into a porphyrin framework. The most significant achievement is the contraction of the six‐membered ring to a pyrrole ring, which is a phenomenon of great interest to researchers in this field.
Paulina Krzyszowska   +5 more
wiley   +1 more source

Total Synthesis of (+)‐Melonine and (+)‐N4‐Oxy Melonine Enabled by an Intramolecular Alkene Diamination Reaction

open access: yesAngewandte Chemie, EarlyView.
A complexity‐generating intramolecular alkene diamination constitutes the pivotal step in the enantioselective synthesis of the title natural products featuring a strained, cage‐like pentacyclic architecture. Abstract Among more than four thousand monoterpene indole alkaloids (MIAs) isolated to date, only a few feature a 2,2,3‐trisubstituted indoline ...
Vincent Goëlo, Qian Wang, Jieping Zhu
wiley   +1 more source

Acetoacetate ameliorates skin fibrosis by modulating TGF-β1-Smad2/3 signaling pathway. [PDF]

open access: yesJ Biol Chem
Shang T   +13 more
europepmc   +1 more source

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