Asymmetric preparation of antifungal 1-(4 -chlorophenyl)-1-cyclopropyl methanol and 1-(4 -chlorophenyl)-2-phenylethanol. Study of the detoxification mechanism by Botrytis cinerea [PDF]
, 2011 Chiral alcohols are important as bioactive compounds or as precursors to such molecules. On the basis of the different antifungal properties of the enantiopure alcohol derivatives of 4-chlorophenyl cyclopropyl ketone and benzyl 4-chlorophenyl ketone ...
Aleu Casatejada, Josefina +4 more
core +2 more sources
Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure
Circulation, 2020 Despite existing therapy, patients with heart failure (HF) experience substantial morbidity and mortality, highlighting the urgent need to identify novel pathophysiological mechanisms and therapies, as well.
S. Selvaraj, D. Kelly, K. Margulies
semanticscholar +1 more source
Cardiorenal ketone metabolism: a positron emission tomography study in healthy humans
Frontiers in Physiology, 2023 Ketones are alternative energy substrates for the heart and kidney but no studies have investigated their metabolism simultaneously in both organs in humans.
Bernard Cuenoud +14 more
doaj +1 more source
Rational design of a (S)-selective-transaminase for asymmetric synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine [PDF]
, 2016 Amine transaminases offer an environmentally sustainable synthesis route for the production of pure chiral amines. However, their catalytic efficiency toward bulky ketone substrates is greatly limited by steric hindrance and therefore presents a great ...
Allen, Christopher C.R. +12 more
core +3 more sources
The Metabolic Effects of Ketones [PDF]
International Journal of Molecular Sciences, 2021 The phrase “once trash, now a treasure” is an apt description of the evolving view of ketones in biomedical research [...]
Benjamin T. Bikman +1 more
openaire +3 more sources
Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease
Nature Network Boston, 2015 The ketone bodies β-hydroxybutyrate (BHB) and acetoacetate (AcAc) support mammalian survival during states of energy deficit by serving as alternative sources of ATP. BHB levels are elevated by starvation, caloric restriction, high-intensity exercise, or
Y. Youm +16 more
semanticscholar +1 more source
Exchange reactions of poly(arylene ether ketone) dithioketals with aliphatic diols: formation and deprotection of poly(arylene ether ketal)s [PDF]
, 2017 The dithioketal derivatives of industrially important, semi-crystalline poly(arylene ether ketone)s undergo facile exchange with aliphatic diols in the presence of N-bromo-succinimide to give a range of novel poly(arylene ether ketal)s.
Colquhoun, Howard +2 more
core +1 more source
A Review on the Catalytic Acetalization of Bio-renewable Glycerol to Fuel Additives
Frontiers in Chemistry, 2018 The last 20 years have seen an unprecedented breakthrough in the biodiesel industry worldwide leads to abundance of glycerol. Therefore, the economic utilization of glycerol to various value-added chemicals is vital for the sustainability of the ...
Amin Talebian-Kiakalaieh +4 more
doaj +1 more source
Molecules, 2021 Over the past several decades, photopolymerization has become an active research field, and the ongoing efforts to develop new photoinitiating systems are supported by the different applications in which this polymerization technique is involved ...
Nicolas Giacoletto, Frédéric Dumur
doaj +1 more source
A Facile One-Pot Process for the Formation of Hindered Tertiary Amines
Molecules, 2012 A simple and convenient method was developed for the preparation of hindered tertiary amines via direct reductive amination of ketones with secondary aryl amines, using trichlorosilane as reducing agent and tetramethylethylenediamine (TMEDA) as organic ...
Jian Sun +4 more
doaj +1 more source