A Human-Curated Annotation of the Candida albicans Genome. [PDF]
PLoS Genetics, 2005 Recent sequencing and assembly of the genome for the fungal pathogen Candida albicans used simple automated procedures for the identification of putative genes.
Burkhard R Braun +42 more
doaj +2 more sources
Fatty Acid Synthetase from Pig Liver [PDF]
European Journal of Biochemistry, 1971 Experimental evidence and theoretical considerations are presented which show that the pure enzyme with oxidoreductase activity for alicyclic ketones which was isolated from pig liver is a fatty acid synthetase. The enzyme exhibits fatty acid synthetase activity with the natural substrates, acetyl‐ and malonyl‐CoA, and when incubated with 14C‐labeled ...
H, Dutler, A, Kull, R, Mislin
openaire +5 more sources
Novel NADP-linked alcohol–aldehyde/ketone oxidoreductase in thermophilic ethanologenic bacteria [PDF]
Biochemical Journal, 1981 An NADP-specific alcohol--aldehyde/ketone oxidoreductase was detected in cell extracts of Thermoanaerobium brockii and Clostridium thermohydrosulfuricum, but not in Thermobacteroides acetoethylicus or Clostridium thermocellum. The enzyme was purified from Ta. brockii by differential procedures that included heat treatment and an affinity-chromatography
R J, Lamed, J G, Zeikus
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Oxidative Medicine and Cellular Longevity, 2023 Nonalcoholic fatty liver disease (NAFLD) has reached epidemic proportions with no pharmacological treatment approved. Several highly accessible computational tools were employed to predict the activities of twelve novel compounds prior to actual chemical synthesis.
Yanan Qiao +10 more
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The characterization of a short chain dehydrogenase/reductase (SDRx) in Comamonas testosteroni
Toxicology Reports, 2020 C. testosteroni is a research topic that can degrade steroid hormones into water and carbon dioxide through a series of enzymes in the body. Short-chain dehydrogenase (SDR) are a class of NAD (P) H-dependent oxidoreductases in C. testosteroni.
Chuanzhi Liu +4 more
doaj +1 more source
Inhibition of oncogenic transcription factor REL by the natural product derivative calafianin monomer 101 induces proliferation arrest and apoptosis in human B-lymphoma cell lines [PDF]
, 2015 Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB.
Chennamadhavuni, Spandan +4 more
core +4 more sources
Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019) [PDF]
, 2019 The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected and synergized. A way to depict that innovation is by conducting a survey on patent activities.
Alcántara, Andrés R. +2 more
core +3 more sources
Regulation of 3β-Hydroxysteroid Dehydrogenase/∆5-∆4 Isomerase: A Review [PDF]
, 2013 This review focuses on the expression and regulation of 3β-hydroxysteroi ddehydrogenase/Δ5-Δ4 isomerase (3β-HSD), with emphasis on the porcine version. 3β-HSD is often associated with steroidogenesis, but its function in the metabolism of both steroids ...
Abbaszade +121 more
core +2 more sources
Recent trends in whole cell and isolated enzymes in enantioselective synthesis [PDF]
, 2011 Modern synthetic organic chemistry has experienced an enormous growth in biocatalytic methodologies; enzymatic transformations and whole cell bioconversions have become generally accepted synthetic tools for asymmetric synthesis.
Maguire, Anita R., Milner, Sinéad E.
core +1 more source
Polyphosphazenes as Tunable and Recyclable Supports To Immobilize Alcohol Dehydrogenases and Lipases: Synthesis, Catalytic Activity, and Recycling Efficiency [PDF]
, 2010 Financial support from the Spanish Ministerio de Ciencia e Innovación (MICINN, Project CTQ2007-61126 and CTQ 2007-61188) is gratefully ...
Carriedo Ule, Gabino Alejandro +4 more
core +2 more sources