Results 61 to 70 of about 17,233 (279)

Hidratação de 2,2-dicloro-1-ariletanonas [PDF]

open access: yes, 1984
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Curso de Pós-Graduação em Físico ...
Zampiron, Eduardo Antônio
core  

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

open access: yesAdvanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Síntese de cristais líquidos quirais contendo a unidade tolano [PDF]

open access: yes, 2000
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaA síntese e a completa caracterização de duas séries de cristais líquidos quirais derivados do (S)-2 ...
Ely, Fernando
core  

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

Analysis of volatile compounds of sour guava ( Psidium acidum [DC.] Landrum) using headspace - solid phase microextraction

open access: yesRevista CENIC Ciencias Químicas, 2021
Application of headspace-solidphase microextraction combined with gas chromatography coupled to flame ionization, mass spectrometry and olfactometric detectors was used to analyze, for the first time, the volatile compounds of sour ...
Jorge A. Pino   +3 more
doaj   +2 more sources

The Combined Analysis of GC-IMS and GC-MS Reveals the Differences in Volatile Flavor Compounds between Yak and Cattle-Yak Meat

open access: yesFoods
In order to investigate the composition and differences in volatile organic compounds (VOCs) in yak and cattle-yak meat and determine the key metabolites and metabolic pathways related to flavor formation.
Ben Zhang   +10 more
doaj   +1 more source

A Strong Lewis Acidic Diethylsilylium Catalyst for Direct Sulfonamidation of Challenging Ketones

open access: yesAdvanced Science, EarlyView.
Low‐substitution‐order silylium ions (R2HSi+) exhibit exceptional Lewis acidic activity. We report diethylsilylium‐catalyzed reductive sulfonamidation of functionalized ketones to access β‐amino esters. The in situ generated ion pair shows enhanced reactivity, with diethylsilane serving as both reductant and precatalyst. The developed protocol proceeds
Woo Hee Kim   +5 more
wiley   +1 more source

Identification of oxygen containing volatiles in cephalic secretions of workers of Brazilian stingless bees

open access: yesJournal of the Brazilian Chemical Society, 2000
The volatile constituents of cephalic secrections of 11 Brazilian social stingless bee species of the Tetragonisca - Tetragona line have been analysed. By gas chromatography/mass spectrometry 145 compounds could be identified which include 72 esters, 22 ...
Francke Wittko   +9 more
doaj  

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

open access: yesAdvanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak   +19 more
wiley   +1 more source

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