Results 71 to 80 of about 30,212 (209)
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]
, 2016 BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core +2 more sources
MedComm, Volume 7, Issue 4, April 2026.This review article provides a comprehensive exploration of the synergistic integration of molecular dynamics (MD) simulations and metal–organic frameworks (MOFs) to advance the design and optimization of nanoscale drug delivery systems (DDSs). We believe this work will be of significant interest to researchers in nanomedicine, computational biology ...
Jiahao Xu +11 more
wiley +1 more source
Preparation and Evaluation of Ketoprofen Nanosuspension Using Solvent Evaporation Technique
Iraqi Journal of Pharmaceutical Sciences, 2017 The effective surface area of drug particle is increased by a reduction in the particle size. Since dissolution takes place at the surface of the solute, the larger the surface area, the further rapid is the rate of drug dissolution ...
Hayder K . Abbas +2 more
doaj +3 more sources
STABILITY OF KETOPROFEN COATED BY CHITOSAN-GUAR GUM GEL
Indonesian Journal of Chemistry, 2010 The coating stability of ketoprofen by chitosan-guar gum gel has been studied. Into 228.6 mL of 1.75% (w/v) chitosan solution in 1% (v/v) acetic acid, 38.1 mL of guar gum (gg) solution was added with concentration variation of 0.35, 0.55, and 0.75% (w/v)
Purwantiningsih Sugita +3 more
doaj +1 more source
Unimolecular branched block copolymer nanoparticles in methanol for the preparation of poorly water-soluble drug nanoparticles [PDF]
, 2017 Unimolecular branched polymer nanoparticles are formed in methanol via a simple thermal annealing process, which can be used to produce aqueous drug nanoparticle suspensions.
He, Tao +7 more
core +1 more source
In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives
ChemistryOpen, Volume 15, Issue 4, April 2026.Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah +13 more
wiley +1 more source
Inhibition of Connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory [PDF]
, 2016 Astrocytes are active players in higher brain function as they can release gliotransmitters, which are essential for synaptic plasticity. Various mechanisms have been proposed for gliotransmission, including vesicular mechanisms as well as non-vesicular ...
Albertini, Giulia +5 more
core +2 more sources
Equine Veterinary Education, Volume 38, Issue 4, Page 206-219, April 2026.Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley +1 more source
International Wound Journal, Volume 23, Issue 4, April 2026.ABSTRACT Hyperbaric oxygen therapy (HBOT) enhances wound healing by promoting angiogenesis and reducing hypoxia. However, the role of air‐breaks—intermittent exposures to ambient air during HBOT—remains unclear. We investigated the effects of air‐breaks on HBOT‐mediated wound healing, particularly in combination with adipose‐derived stromal cells (ASCs)
Eun Hee Ha +6 more
wiley +1 more source