Results 71 to 80 of about 103,973 (310)

We develop key competencies: interdisciplinary aspect [PDF]

open access: yes, 2020
У статті розкрито основні поняття компетентнісної освіти. Подано перелік наскрізних життєво необхідних ключових компетентностей, які мають формуватися на уроках з усіх предметів.
Бондаренко, Неллі Володимирівна
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Актуальность развития презентационной компетентности субъекта в условиях VUCA-мира

open access: yesНаучно-педагогическое обозрение
Трансформация традиционной образовательной парадигмы, преобладавшей до конца XX в., была вызвана глобальными системными изменениями во всех сферах жизни человека.
Гадалов Демид Игоревич
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Key competency development and students use of digital learning objects

open access: yes, 2012
The inclusion of key competencies in the New Zealand Curriculum (2007) has presented challenges for teachers in their efforts to gather evidence and detail student progress for reporting purposes.
Falloon, Garry
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Sustainability competencies in the workplaces: A systematic review

open access: yesSustainable Futures
In past decades, a growing body of research has identified sustainability competencies as a pivotal element in the process of sustainability transition. However, the topic is mainly discussed in the educational field, and few studies have investigated it
Lu Fu, Ulla Kemi, Ilkka Ratinen
doaj   +1 more source

Les contenus linguistiques dans les référentiels et les discours des formateurs. Définitions, conceptions et références

open access: yesLidil, 2012
This article analyzes the linguistic contents presented in four reference models linguistic standards used in teacher education in the areas of “basic knowledge” and “key competencies” and in the discourse  of adult teacher educators.
Marie-Cécile Guernier
doaj   +1 more source

Ranking workplace competencies: Student and graduate perceptions

open access: yes, 2002
Students and graduates from a variety of business studies programs at a New Zealand tertiary institution completed a questionnaire in which they ranked the relative importance of a list of 24 competencies for graduates entering the workforce using a 7 ...
Burchell, Noel   +3 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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