Results 51 to 60 of about 6,155,073 (278)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

High-Speed Key Encapsulation from NTRU

, 2017
This paper presents software demonstrating that the 20-year-old NTRU cryptosystem is competitive with more recent lattice-based cryptosystems in terms of speed, key size, and ciphertext size. We present a slightly simplified version of textbook NTRU, select parameters for this encryption scheme that target the 128-bit post-quantum security level ...
Andreas Hülsing, Joost Rijneveld, John M. Schanck, Peter Schwabe   +3 more
openaire   +4 more sources

Identity-based online/offline key encapsulation and encryption [PDF]

Proceedings of the 6th ACM Symposium on Information, Computer and Communications Security, 2011
An identity-based online/offline encryption (IBOOE) scheme splits the encryption process into two phases. The first phase performs most of the heavy computations, such as modular exponentiation or pairing over points on elliptic curve. The knowledge of the plaintext or the receiver's identity is not required until the second phase, where the ciphertext
Sherman S. M. Chow, Joseph K. Liu, Jianying Zhou 0001   +2 more
openaire   +3 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Efficient and provably secure attribute-based online/offline encryption schemes

Tongxin xuebao, 2014
To improve the encryption efficiency, the online/offline cryptography was extended to ABE and the primitive of attribute-based online/offline encryption (ABOOE) was proposed.
Hai-ying MA, Guo-sun ZENG, GZhan-jun WAN, Wei WANG   +3 more
doaj  

High-speed Instruction-set Coprocessor for Lattice-based Key Encapsulation Mechanism: Saber in Hardware

Transactions on Cryptographic Hardware and Embedded Systems, 2020
In this paper, we present an instruction set coprocessor architecture for lattice-based cryptography and implement the module lattice-based post-quantum key encapsulation mechanism (KEM) Saber as a case study.
Sujoy Sinha Roy, Andrea Basso
doaj   +1 more source

Tissue Regeneration with Hydrogel Encapsulation: A Review of Developments in Plants and Animals

BioDesign Research, 2021
Hydrogel encapsulation has been widely utilized in the study of fundamental cellular mechanisms and has been shown to provide a better representation of the complex in vivo microenvironment in natural biological conditions of mammalian cells.
Srikumar Krishnamoorthy, Michael F. Schwartz, Lisa Van den Broeck, Aitch Hunt, Timothy J. Horn, Rosangela Sozzani   +5 more
doaj   +1 more source

Implementation of a leakage-resilient ElGamal key encapsulation mechanism [PDF]

Journal of Cryptographic Engineering, 2016
Leakage-resilient cryptography aims to extend the rigorous guarantees achieved through the provable security paradigm to physical implementations. The constructions designed on basis of this new approach inevitably suffer from an Achilles heel: a bounded leakage assumption is needed.
David Galindo, Johann Großschädl, Zhe Liu 0001, Praveen Kumar Vadnala, Srinivas Vivek 0001   +4 more
openaire   +4 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source