Results 241 to 250 of about 361,970 (307)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Reproducibility, validation, and failure modes across classical and AI-driven molecular docking. [PDF]

J Comput Aided Mol Des
Kittelson KS, Martins ACF, Santos RP, Celante G, da Silva Gomes R.   +4 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

<i>N</i>-nitroamine: Open a new era for direct deaminative functionalization. [PDF]

Innovation (Camb)
Li HY, Zhu CM, Li JL, Meng QY.
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

TTEA: designing a quantum-ready and energy-conscious encryption model for secure IoT environments. [PDF]

Sci Rep
Abdelaal MA, Moustafa AI, Saleh H, Afifi MYI.   +3 more
europepmc   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Trends in recorded deaths involving antipsychotics: The role of deprivation, ethnicity, and regional disparities. [PDF]

PLoS One
Khan MU, Hasan SS.
europepmc   +1 more source

AI-Driven De Novo Binder Design: From Structure Prediction to Closed-Loop Optimization. [PDF]

Comput Struct Biotechnol J
Li X, Fan Z, Yang J, Jiang R, Cao F, Li J, Xie D, Meng X, Sun M, Wang L.   +9 more
europepmc   +1 more source

Light-curing units in restorative dentistry: a clinically oriented narrative review of performance, selection, and emerging optical functions. [PDF]

BDJ Open
Ceinos R, Dubois M, Attal JP, Vigouroux F, Flottes Y, Fasham T, Dursun E, Pelissier B, D'Agostino MA, François P.   +9 more
europepmc   +1 more source