Results 91 to 100 of about 6,638,555 (335)

Theoretical Aspects of Molecular Recognition [PDF]

open access: yes, 2009
Molecular recognition is a key process in non-covalent interactions, which determines, among others, host-guest complexation, drug action and protein-protein interaction. A simple and attractive formulation is the lock-and-key analogy defining the host
Harmat, Veronika, Náray-Szabó, Gábor
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Safe and smooth through a shallow fairway [PDF]

open access: yes, 2010
Since the ever growing dimensions of all vessel types coming to the Flemish harbours which started in the mid 80’s of last century, the research at Flanders Hydraulics Research, a laboratory belonging to the Flemish Government, concerning harbour ...
Eloot, Katrien, Lataire, Evert
core   +1 more source

From Lock Freedom to Progress Using Session Types [PDF]

open access: yes, 2013
Inspired by Kobayashi's type system for lock freedom, we define a behavioral type system for ensuring progress in a language of binary sessions. The key idea is to annotate actions in session types with priorities representing the urgency with which such
Padovani, Luca
core   +3 more sources

The size-selective interaction of key and lock nanocrystals driven by depletion attraction at the nanoscale.

open access: yesNanoscale, 2018
In this article, we study the size-dependent interactions of quasi-spherical nanocrystals with voids of concave nanoparticles of complementary sizes and shapes.
Dominik Hinrichs   +2 more
semanticscholar   +1 more source

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

open access: yesAdvanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams   +7 more
wiley   +1 more source

Verrouillage professionnel

open access: yesRevue d'anthropologie des connaissances, 2014
Recent challenges such as sustainable development and climate change suggest engineers to focus on societal issues. However, as this case study of structural design shows, professional arrangements within the construction field constrain engineers ...
Andrew Chilvers, Sarah Bell
doaj   +1 more source

Censorship: the Key to Lock-In? [PDF]

open access: yes
Markets for information and entertainment are frequently characterized by increasing returns to scale in production and distribution. This implies that incumbent technologies enjoy an advantage over newcomer technologies; such markets can become locked ...
Brendan M. Cunningham
core  

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

Assembling oppositely charged lock and key responsive colloids: A mesoscale analog of adaptive chemistry

open access: yesScience Advances, 2017
Oppositely charged thermoresponsive particles with complementary geometries are assembled into adaptive colloidal molecules. We have seen a considerable effort in colloid sciences to copy Nature’s successful strategies to fabricate complex functional ...
A. Mihut   +4 more
semanticscholar   +1 more source

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