Results 151 to 160 of about 11,653,432 (296)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Streetscape, Williams Avenue, Queenstown [picture].

open access: yes, 1995
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892265 ...
Key, Mike, 1951-
core  

Key Performance Parameters

open access: yes
This deliverable will include the formulated key performance parameters that will be utilized during the project for verification and validation processes.
openaire   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

'Miners Siding' sculpture, Driffield Street, Queenstown [picture].

open access: yes, 1995
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892265 ...
Key, Mike, 1951-
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Design of Key Parameters of Extended Drillpipe

open access: yesShiyou jixie
Extended drillpipe is an important drilling tool that uses very few collars. When applied to complex wells (e.g. deep wells and long horizontal wells), it can effectively reduce operational risks that are possibly induced by failure incidents at ...
Xu Zhaohui   +4 more
doaj  

New Norfolk Bowling Club, Esplanade [picture].

open access: yes, 1995
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892270 ...
Key, Mike, 1951-
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Old housing, renovated and used as professional premises, 18-22 Brisbane Street, Launceston [picture] /

open access: yes, 1995
Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892262 ...
Key, Mike, 1951-
core  

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