Results 121 to 130 of about 309,055 (245)

Lessons from implementation of a nephrology key performance indicator programme. [PDF]

Intern Med J
Steinberg AG, Mount PF, Branagan M, Roberts MA, Toussaint ND.   +4 more
europepmc   +1 more source

Key performance indicators for the indoor environment

, 2011
The overall quality of the indoor environment in which people live, work and spend their time and artefacts remain, is the result from a complex integration of a large number of physical attributes. These attributes result from an integration of a large number of building components.
Loomans, M.G.L.C., Huovila, Aapo, Lefebvre, Pierre-Henri, Porkka, Janne, Huovila, Pekka, Desmyter, Jan, Vaturi, Asher   +6 more
openaire   +3 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

What Clinical Pharmacy Key Performance Indicator Processes of Care Were Patients Receiving across Canada in 2018? A National Patient Registry and Pooled Analysis. [PDF]

Can J Hosp Pharm
Carroccia A, Fernandes OA, Toombs K, Gorman SK, Spina SP, Semchuk WM, Meade A, Lowe D, Bayoud T, Shalansky S, Facca NM, Seto W, Bussières JF, Wong GG, Lui P, Slavik RS, Doucette D, Latariya G, Chant C.   +18 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Development of a key performance indicator set for perioperative red blood cell transfusion. [PDF]

BJA Open
Shah A, Evans HG, Palmer AJR, MacDonald AM, Belete M, von Neree L, Murphy MMF, Stanworth SJ, Foy R, NIHR Blood and Transplant Research Unit in Data Driven Transfusion Practice.   +9 more
europepmc   +1 more source

Overall Key Performance Indicator to Optimizing Operation of High-Pressure Homogenizers for a Reliable Quantification of Intracellular Components in Pichia pastoris. [PDF]

Front Bioeng Biotechnol, 2015
Garcia-Ortega X, Reyes C, Montesinos JL, Valero F.   +3 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Enhancing the use of sodium-glucose cotransporter-2 inhibitors in type-2 diabetic patients with chronic kidney disease, through a key performance indicator program. [PDF]

Qatar Med J
Asim M, Abdul Rahiman R, Abdul Azim Baig M, Al-Malki H.   +3 more
europepmc   +1 more source