Characterization and expression analysis of UBC gene family provide insights into the potential roles in pigment biosynthesis in pepper fruit. [PDF]
Jia L +9 more
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The GhWRKY70-<i>GhAOS1</i> Axis Integrates Jasmonate Pathway Signaling to Regulate Cotton Immunity Against <i>Verticillium dahliae</i>. [PDF]
Weng H +6 more
europepmc +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Urban Spontaneous Plants and Vegetation: Advantages and Management Challenges. [PDF]
Bretzel F, Romano D.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
A novel Sinomonas strain and Its genus-wide genomic insights into plant growth-promoting potential. [PDF]
Wu H +12 more
europepmc +1 more source
The impact of fertilization on the health of paddy soil: pathways and prospects for fertility regulation based on microbial communities. [PDF]
Xu H +9 more
europepmc +1 more source
Editorial: Biofabrication and synthetic biology for enhanced medicinal plant bioproduction. [PDF]
Ahmad Z, Faisal M, Martinez-Montero ME.
europepmc +1 more source

