Results 101 to 110 of about 10,030,622 (339)

Post tsunami recovery capacity gaps in Sri Lanka [PDF]

open access: yes
Poor response capacity has been identified as a major inhibitor for successful post tsunami recovery attempts in Sri Lanka. Despite level of incentives aid and help which have been received from the international communities, both governmental and ...
Amaratunga, Dilanthi   +2 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Resilient Quantum Key Distribution (QKD)-Integrated Optical Networks With Secret-Key Recovery Strategy

open access: yesIEEE Access, 2019
Quantum key distribution (QKD) promises to deliver secure keys, which can be applied for security demands in optical networks by using cost-efficient and scalable lightpaths.
Hua Wang   +7 more
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

On Decoding Schemes for the MDPC-McEliece Cryptosystem [PDF]

open access: yes, 2018
Recently, it has been shown how McEliece public-key cryptosystems based on moderate-density parity-check (MDPC) codes allow for very compact keys compared to variants based on other code families. In this paper, classical (iterative) decoding schemes for
Bartz, Hannes, Liva, Gianluigi
core   +1 more source

Fountain Codes with Nonuniform Selection Distributions through Feedback

open access: yes, 2015
One key requirement for fountain (rateless) coding schemes is to achieve a high intermediate symbol recovery rate. Recent coding schemes have incorporated the use of a feedback channel to improve intermediate performance of traditional rateless codes ...
Cassuto, Yuval   +2 more
core   +1 more source

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