Results 81 to 90 of about 338,284 (271)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Estimating moose population parameters from aerial surveys [PDF]
, 1986 Successful moose management depends on knowledge of population dynamics. The principal parameters required are size, rate of change, recruitment, sex composition, and mortality.
DuBois, Stephen D. +3 more
core
Procedia Engineering, 2012 AbstractThe overburden movement in cemented backfill mining is different from what it is in traditional longwall mining. This paper analyses the overburden movement in cemented backfill mining by using computer simulated model, observes the overburden movement in different mining advances distance, compares to traditional longwall mining and finds the ...
Li, Yang, Qiu, Biao
openaire +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Frontiers in Earth ScienceTargeting the “two hard and one soft” overlying strata (fine sandstone, siltstone, and coal seam) of the 5th coal seam in Yanbei Coal Mine, Huating Mining Area, this study investigates the influence of key strata on strata movement and rock pressure ...
Wang Jindong, Fu Jiayao, Guo Shuchao
doaj +1 more source
Intersection Homology. General perversities and topological invariance
, 2019 Topological invariance of the intersection homology of a pseudomanifold without codimension one strata, proven by Goresky and MacPherson, is one of the main features of this homology. This property is true for codimension-dependent perversities with some
Chataur, David +2 more
core +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Influence of Key Strata on the Gas Downward Leakage Law in Dual-System of Coal Seam
Geofluids, 2020 In Datong mining area, CO and other harmful gases were discharged from the gob in the Jurassic overburden strata to the panel of Carboniferous coal seam.
Feng Du, Kun Jiao, Zhanyuan Ma
doaj +1 more source
Simple normal crossing varieties with prescribed dual complex [PDF]
, 2013 We prove that every simplicial complex is the dual complex of some simple normal crossing divisor in a smooth variety. As an application, we simplify and extend the results of Kapovich--Koll\'ar (math.AG:1109.4047) on the existence of singularities with ...
Kollár, János
core
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source