Results 41 to 50 of about 4,197 (217)

Offloading Key Switching on GPUs: A Path towards Seamless Acceleration of FHE [PDF]

open access: yes2025 IEEE International Conference on Cyber Security and Resilience (CSR)
Fully Homomorphic Encryption (FHE) enables secure computations on encrypted data, offering strong privacy guarantees for cloud computing, privacy-preserving machine learning, and confidential data processing. However, the computational overhead associated with FHE operations, due to the large size of ciphertext and the high arithmetic complexity ...
Papadakis, Orion   +5 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

NOMA-Aided UAV Data Collection System: Trajectory Optimization and Communication Design

open access: yesIEEE Access, 2020
Unmanned aerial vehicle (UAV) communication has been deemed as a promising technology to collect data for the Internet of Things (IoT) in inaccessible areas.
Junwei Zhao   +4 more
doaj   +1 more source

Optimizing Key Consumption in Switched QKD Networks

open access: yesOptical Fiber Communication Conference (OFC) 2024
We consider a switched QKD network and develop a novel scheduling algorithm that periodically configures the QKD links to optimize the generation and buffering of keys to maximize the key consumption rate across the network.
Christodoulopoulos, Konstantinos   +3 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Ubiquitous memory augmentation via mobile multimodal embedding system

open access: yesNature Communications
Forgetting is inevitable in human memory. Recently, multimodal embedding models have been proposed to vectorize multimodal reality into a unified embedding space.
Dongqi Cai   +7 more
doaj   +1 more source

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