Results 41 to 50 of about 4,197 (217)
Offloading Key Switching on GPUs: A Path towards Seamless Acceleration of FHE [PDF]
Fully Homomorphic Encryption (FHE) enables secure computations on encrypted data, offering strong privacy guarantees for cloud computing, privacy-preserving machine learning, and confidential data processing. However, the computational overhead associated with FHE operations, due to the large size of ciphertext and the high arithmetic complexity ...
Papadakis, Orion +5 more
openaire +3 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
NOMA-Aided UAV Data Collection System: Trajectory Optimization and Communication Design
Unmanned aerial vehicle (UAV) communication has been deemed as a promising technology to collect data for the Internet of Things (IoT) in inaccessible areas.
Junwei Zhao +4 more
doaj +1 more source
Optimizing Key Consumption in Switched QKD Networks
We consider a switched QKD network and develop a novel scheduling algorithm that periodically configures the QKD links to optimize the generation and buffering of keys to maximize the key consumption rate across the network.
Christodoulopoulos, Konstantinos +3 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Ubiquitous memory augmentation via mobile multimodal embedding system
Forgetting is inevitable in human memory. Recently, multimodal embedding models have been proposed to vectorize multimodal reality into a unified embedding space.
Dongqi Cai +7 more
doaj +1 more source

