Results 41 to 50 of about 6,283,030 (299)

Mission-Critical Resource Allocation With Puncturing in Industrial Wireless Networks Under Mixed Services

IEEE Access, 2021
As the manufacturing industry gradually expands and tends to be intelligent, the industrial networks have been greatly applied and are of paramount importance.
Weichen Ning, Ying Wang, Man Liu, Yuanbin Chen, Xue Wang   +4 more
doaj   +1 more source

Src activation by β-adrenoreceptors is a key switch for tumour metastasis [PDF]

Nature Communications, 2013
Noradrenaline can modulate multiple cellular functions important for cancer progression; however, how this single extracellular signal regulates such a broad array of cellular processes is unknown. Here we identify Src as a key regulator of phosphoproteomic signalling networks activated in response to beta-adrenergic signalling in cancer cells.
Guillermo N, Armaiz-Pena, Julie K, Allen, Anthony, Cruz, Rebecca L, Stone, Alpa M, Nick, Yvonne G, Lin, Liz Y, Han, Lingegowda S, Mangala, Gabriel J, Villares, Pablo, Vivas-Mejia, Cristian, Rodriguez-Aguayo, Archana S, Nagaraja, Kshipra M, Gharpure, Zheng, Wu, Robert D, English, Kizhake V, Soman, Mian M K, Shahzad, Mian M K, Shazhad, Maya, Zigler, Michael T, Deavers, Alexander, Zien, Theodoros G, Soldatos, David B, Jackson, John E, Wiktorowicz, Madeline, Torres-Lugo, Tom, Young, Koen, De Geest, Gary E, Gallick, Menashe, Bar-Eli, Gabriel, Lopez-Berestein, Steve W, Cole, Gustavo E, Lopez, Susan K, Lutgendorf, Anil K, Sood   +33 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A-ECN Minimizing Queue Length for Datacenter Networks

IEEE Access, 2020
Recently, Explicit Congestion Notification (ECN) has been leveraged by DCTCP and its successive protocols to reduce the latency in datacenters. However, we find that DCTCP may induce the queue underflow and high latency in multi-queue scenarios and even ...
Shuo Wang, Jiao Zhang, Tao Huang, Tian Pan, Jiang Liu, Yunjie Liu   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Nod-Like Receptors: Key Molecular Switches in the Conundrum of Cancer [PDF]

Frontiers in Immunology, 2014
It is believed the immune system can contribute to oncogenic transformation especially in settings of chronic inflammation, be activated during immunosurveillance to destroy early neoplastic cells before they undergo malignant outgrowth, and finally, can assist growth of established tumors by preventing clearance, remodeling surrounding tissue, and ...
Kent, Andrew, Blander, J. Magarian
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Optimizing Key Consumption in Switched QKD Networks

Optical Fiber Communication Conference (OFC) 2024
We consider a switched QKD network and develop a novel scheduling algorithm that periodically configures the QKD links to optimize the generation and buffering of keys to maximize the key consumption rate across the network.
Christodoulopoulos, Konstantinos, Makris, Nikolaos, Kanellos, George T., Syvridis, Dimitris   +3 more
openaire   +2 more sources

Offloading Key Switching on GPUs: A Path towards Seamless Acceleration of FHE [PDF]

2025 IEEE International Conference on Cyber Security and Resilience (CSR)
Fully Homomorphic Encryption (FHE) enables secure computations on encrypted data, offering strong privacy guarantees for cloud computing, privacy-preserving machine learning, and confidential data processing. However, the computational overhead associated with FHE operations, due to the large size of ciphertext and the high arithmetic complexity ...
Papadakis, Orion, Papadimitriou, Michail, Stratikopoulos, Athanasios, Xekalaki, Maria Nektaria, Fumero, Juan, Kotselis, Christos   +5 more
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source