Results 71 to 80 of about 6,561,343 (302)

Personalized Sketch-Based Image Retrieval by Convolutional Neural Network and Deep Transfer Learning

IEEE Access, 2019
The sketch-based image retrieval (SBIR) finds the natural images according to the features and rules defined by human beings. The retrieval results are generally similar in contour; however, their complete semantic information of the image is missing ...
Qi Qi, Qiming Huo, Jingyu Wang, Haifeng Sun, Yufei Cao, Jianxin Liao   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

CALENDAR+: in-context contrastive learning for temporal knowledge graph reasoning

Complex & Intelligent Systems
Temporal Knowledge Graph (TKG) reasoning aims to infer future events from historical facts. Recent advances in large language models (LLMs) have shown that in-context learning can effectively enhance temporal reasoning.
Xingyi Li, Jiapeng Wang, Boyuan Jia, Xiang Cheng, Sen Su   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Developmental switches that hold the key to a revolution in crop biotechnology [PDF]

Nature Reviews Genetics, 2011
1have provided valuable insights into transcriptional regulation during well-known developmental switches in Arabidopsis thaliana — including the development of the inflorescence meristem from the apical meristem and the establishment of floral organ identities.
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Code-switching

, 2018
Dataset for the study How does Code-switching while Giving Instructions in Chinese EFL ...
Xiuzhen Xiong (5153552)
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

"Optical code label switching and its applications, invited paper at Photonics in Switching, Herakleion Greece, 2006

, 2006
With current mature optical device technology for processing optical codes (OCs), OC label switchings now become promising for the future photonic networkings.
CINCOTTI, GABRIELLA, ONAKA H., KATAOKA N., YOSHIMA S., KITAYAMA K.   +4 more
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source