Results 1 to 10 of about 12,145 (232)

Biological activities of limonoids in the Genus Khaya (Meliaceae): a review

Future Journal of Pharmaceutical Sciences, 2021
Background Limonoids are a class of highly oxygenated modified triterpenoids with a diverse range of biological activities. Although with restricted occurrence in the plant kingdom, these compounds are found extensively in the Meliaceae and Rutaceae ...
Tomi Lois Olatunji, Christiana Adeyinka Odebunmi, Ademola Emmanuel Adetunji   +2 more
doaj   +2 more sources

Antiplasmodial and Antileishmanial Activities of a New Limonoid and Other Constituents from the Stem Bark of Khaya senegalensis. [PDF]

Molecules, 2023
Plasmodium falciparum and Leishmania sp. resistance to antiparasitic drugs has become a major concern in malaria and leishmaniasis control. These diseases are public health problems with significant socioeconomic impacts, and mostly affect disadvantaged ...
Amang À Ngnoung GA, Nganso Ditchou YO, Leutcha PB, Dize D, Tatsimo SJN, Tchokouaha LRY, Kowa TK, Tembeni B, Mamoudou H, Poka M, Demana PH, Siwe Noundou X, Fekam Boyom F, Meli Lannang A.   +13 more
europepmc   +2 more sources

Antiplasmodial, Antioxidant and Cytotoxicity Activity of Ethanol and Aqueous Extracts of Khaya grandifoliola Stem Bark. [PDF]

J Trop Med, 2023
Background Malaria is a serious public health problem, especially in sub-Saharan Africa. The aim of this study was to scientifically provide baseline information on the use of Khaya grandifoliola stem bark as an antimalaria drug by traditional healers ...
Guy-Armand GN, Cedric Y, Christelle Nadia NA, Azizi MA, Aboubakar Sidiki NN, Jemimah Sandra TN, Alex Kevin TD, Payne VK.   +7 more
europepmc   +2 more sources

Assessment of the antibacterial effect of Khaya senegalensis on some Gram-negative bacteria

Bulletin of the National Research Centre, 2021
Background The matter of antimicrobial resistance evokes the urgency to explore alternatives to the antibiotics traditionally used for microbial infections.
Victorien Dougnon, Edna Hounsa, Hornel Koudokpon, Eric Agbodjento, Anny Afaton, Kevin Sintondji, Jean Robert Klotoe, Julien Segbo, Lamine Baba-Moussa   +8 more
doaj   +2 more sources

Glena bipennaria bipennaria and Apatelodes pandara (Lepidoptera): new defoliating insects associated with Khaya in Brazil

Pesquisa Florestal Brasileira
The expansion of African mahogany (Khaya spp.) plantations in Brazil has led to an increase in the number of associated insect pests. Here we report the first instances of defoliating caterpillars [Glena bipennaria bipennaria (Guenée) (Geometridae) and ...
Luana de Souza Covre, Robert A. Haack, Carlos Alberto Hector Flechtmann   +2 more
doaj   +2 more sources

Khaya grandifololia exerts multitarget neuroprotective potential against neurodegenerative disorders: In vitro and in silico studies [PDF]

IBRO Neuroscience Reports
Background: Treatment for complex multifactorial neurological disorders may benefit more from multifunctional chemicals. Dysregulation of monoaminergic pathways and neuroinflammation are typical confluence points in a range of neuropsychiatric and ...
Fils Armand Ella, Bruno Dupon Akamba Ambamba, Frederic Nico Njayou, Paul Fewou Moundipa   +3 more
doaj   +2 more sources

In Vitro Anthelmintic Activities of Khaya anthotheca and Faidherbia albida Extracts Used in Chad by Traditional Healers for the Treatment of Helminthiasis and In Silico Study of Phytoconstituents. [PDF]

J Trop Med
Background Helminthiasis is endemic in Chad and constitutes a public health problem, particularly among school-age children. The aim of this study was to evaluate the anthelmintic activity of extracts of Khaya anthotheca and Faidherbia albida used in ...
Christalin B, Besati M, Christelle Nadia NA, Yaghoobi M, Cédric Y, Ciancia C, Abdel Azizi M, Guy-Armand GN, Khan Payne V, Hu H.   +9 more
europepmc   +2 more sources

Genetic resources of African mahogany in Brazil: genomic diversity and structure of forest plantations [PDF]

BMC Plant Biology
Background African mahogany species (Khaya sp.) have been introduced to Brazil gaining increasing economic interest over the last years, as they produce high quality wood for industrial applications.
Júlio Cézar Tannure Faria, Enéas Ricardo Konzen, Marcos Vinicius Winckler Caldeira, Tiago de Oliveira Godinho, Luciana Prata Maluf, Sarah Ola Moreira, Carolina da Silva Carvalho, Bárbara Simões Santos Leal, Cássia dos Santos Azevedo, Dione Richer Momolli, Gracielle Teodora da Costa Pinto Coelho, Conceição de Maria Batista de Oliveira, Taís Cristina Bastos Soares   +12 more
doaj   +2 more sources

In Vitro Antischistosomal Activity of Bridelia ferruginea, Clausena anisata, Khaya senegalensis, and Vernonia amygdalina [PDF]

Journal of Tropical Medicine
Background. Schistosomiasis is caused by parasitic flatworms and the disease is endemic to most countries in sub-Saharan Africa including Ghana. The current therapeutic agent for managing this disease solely relies on praziquantel.
Deryl Nii Okantey Kuevi, Jennifer Keiser, Cécile Häberli, Abena Konadu Owusu-Senyah, Mawutor Kwame Ahiabu   +4 more
doaj   +2 more sources

Efficacy of Khaya grandifoliola Stem Bark Ethanol Extract in the Treatment of Cerebral Malaria in Swiss albino Mice Using Plasmodium berghei NK65 Strain [PDF]

Journal of Parasitology Research, 2023
Background. Cerebral malaria is one of the most severe and dangerous forms of malaria and is potentially fatal. This study was aimed at evaluating the anticerebral malaria efficacy of Khaya grandifoliola used by traditional healers. Method.
Gamago Nkadeu Guy-Armand, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Tako Djimefo Alex Kevin, Tientcheu Noutong Jemimah Sandra, Ngouyamsa Nsapkain Aboubakar Sidiki, Mounvera Abdel Azizi, Vincent Khan Payne   +7 more
doaj   +2 more sources