Results 51 to 60 of about 1,866 (175)

Renal Impairment Does Not Affect Pharmacokinetics, Safety or Tolerability of Zenagamtide

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8946-8954, October 2026.
ABSTRACT Aims Zenagamtide is a novel, unimolecular glucagon‐like peptide‐1 and amylin receptor agonist in development for weight management and Type 2 diabetes. This study investigated the pharmacokinetic (PK) properties, safety and tolerability of zenagamtide in participants with various degrees of renal impairment versus participants with normal ...
Lykke Ida Kaas Oldenburg, Sine Pfeiffer Haugaard, Tobias Karlsson, Victoria Kegel‐Hübner, Mahera Parwez, Christoffer Wiingaard, Anne Flint   +6 more
wiley   +1 more source

Susceptibility of stone loach (Barbatula barbatula) and hybrids between sterlet (Acipenser ruthenus) and beluga (Huso huso) to cyprinid herpesvirus 3

Veterinární Medicína, 2016
Cyprinid herpesvirus 3 also known as koi herpesvirus is a causative agent of highly contagious disease (koi herpesvirus disease) and can cause significant losses in fish stocks.
A. Pospichal, V. Piackova, D. Pokorova, T. Vesely   +3 more
doaj   +1 more source

Time‐Efficient Columnar‐to‐Equiaxed Transition via High Magnetic Field Processing

Rare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT The need to simplify processing routes and improve processing efficiency motivates the development of time‐efficient methods for inducing the columnar‐to‐equiaxed transition (CET) during solidification while tailoring material performance. Conventional multistep CET approaches are time‐consuming and often struggle to simultaneously regulate ...
Chendong Zhao, Jun Wang, Yujie Yan, Dou Li, Bijun Tang, Ruihuan Duan, Qingfeng Wu, Zhijun Wang, Tie Liu, Qiang Wang, William Yi Wang, Jinshan Li, Zheng Liu   +12 more
wiley   +1 more source

DNA–Peptide Crosslinks Placed at Codon 249 of the p53 Tumor Suppressor Gene Induce G to A Transitions in Human Cells

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
DNA‐peptide cross‐links (DpCs) are ubiquitous DNA lesions that form when cellular proteins become covalently trapped on DNA strands and are processed by proteases. DpCs are hypothesized to play a role in antitumor activity of chemotherapeutic drugs and to contribute to aging.
Priscilla Yawson, Jan Henric T. Bacurio, Honnaiah Vijay Kumar, Natalia Y. Tretyakova, Ashis K. Basu   +4 more
wiley   +1 more source

Structured Energy Conversion in Kelvin‐Helmholtz Instability

Geophysical Research Letters, Volume 53, Issue 15, 16 August 2026.
Abstract We present quantitative investigations of the energy conversion pathways—electromagnetic ϵEM $\left({{\epsilon}}^{EM}\right)$, fluid flow ϵf $\left({{\epsilon}}^{f}\right)$, and particle thermal ϵth $\left({{\epsilon}}^{th}\right)$ energies—within the Kelvin‐Helmholtz instability (KHI) observed by the Magnetospheric Multiscale mission. We find
Kyunghwan Dokgo, Kyoung‐Joo Hwang, Eunjin Choi, James L. Burch, Rungployphan Kieokaew   +4 more
wiley   +1 more source

Breeding and Seed Production of Aquaculture Species in Bangladesh: Current Status, Challenges and Prospects

Aquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT Aquaculture has become one of the fastest‐growing food production sectors in Bangladesh and contributes significantly to food security, nutrition, livelihoods and the national economy. In Bangladesh, aquaculture mainly relies on the culture of major carps, catfishes and shrimp, which are also widely farmed across Asia and other parts of the ...
Zakiur Rahman Sarker, Ilias Ahmed, Mohammad Abu Baker Siddique, Mohammad Mahfujul Haque, A. K. Shakur Ahammad   +4 more
wiley   +1 more source

Early KHV detection by 7 PCRs

, 2014
Koi herpesvirus (KHV) causes an economically important, highly infectious disease in common carp and koi, Cyprinus carpio L. Since the occurrence of mass mortalities worldwide, highly specific and sensitive molecular diagnostic methods have been ...
Adams, Alexandra, Thompson, Kimberly, S M Bergmann, S J Monaghan, Thompson, K.D., A Adams, Monaghan, Sean, Bergmann, Sven, Bergmann, Sven M, K D Thompson, Adams, A., Monaghan, S.J.   +11 more
core   +1 more source

Tests for the presence of koi herpesvirus (KHV) in common carp (Cyprinus carpio carpio) and koi carp (Cyprinus carpio koi) in the Czech Republic

Veterinární Medicína, 2007
An outbreak of koi herpesvirus (KHV) infection associated with high mortality of common and koi carp was recorded in the USA and Israel in 1998. At present, this disease is viewed as one of the most significant factors that can adversely affect common ...
D. Pokorova, V. Piackova, A. Cizek, S. Reschova, J. Hulova, M. Vicenova, T. Vesely   +6 more
doaj   +1 more source

Structural variation turnovers and defective genomes: key drivers for the in vitro evolution of the large double-stranded DNA koi herpesvirus (KHV)

Peer Community Journal, 2022
Structural variations (SVs) constitute a significant source of genetic variability in virus genomes. Yet knowledge about SV variability and contribution to the evolutionary process in large double-stranded (ds)DNA viruses is limited. Cyprinid herpesvirus
Fuandila, Nurul Novelia, Gosselin-Grenet, Anne-Sophie, Tilak, Marie-Ka, Bergmann, Sven M, Escoubas, Jean-Michel, Klafack, Sandro, Lusiastuti, Angela Mariana, Yuhana, Munti, Fiston-Lavier, Anna-Sophie, Avarre, Jean-Christophe, Cherif, Emira   +10 more
doaj   +1 more source

Intravenous Oxytocin Has no Effect on Ad Libitum Food Intake or Postprandial Plasma Glucose Concentrations in Individuals With Obesity: A Randomised, Placebo‐Controlled, Double‐Blind, Crossover Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4671-4682, June 2026.
ABSTRACT Introduction Oxytocin is expressed throughout the small intestine, suggesting a role for oxytocin in postprandial metabolism. Accordingly, single‐dose intranasal oxytocin reduces food intake and improves glucose tolerance. We investigated the effects of a continuous intravenous oxytocin infusion on ad libitum food intake, appetite sensations ...
Ida M. Gether, Vivian Kliim‐Hansen, Petur T. Olafsson, Miriam G. Pedersen, Casper K. Nielsen, Anne‐Marie Ellegaard, Mikkel B. Christensen, Jens F. Rehfeld, Jørn W. Helge, Jens J. Holst, Bolette Hartmann, Filip K. Knop, Lærke S. Gasbjerg, Asger B. Lund   +13 more
wiley   +1 more source