Results 51 to 60 of about 137,214 (262)

Upregulation of Endothelin-1/Endothelin A Receptor Expression Correlates with Heparanase Expression in Ovarian Carcinoma

Iranian Journal of Medical Sciences, 2018
Background: Heparanase and endothelin-1/endothelin A receptor (ET-1/ETAR) expressions increase in cancer. This condition enhances tumor progression and correlates with poor survival.
Nungki Anggorowati, Ahmad Ghozali, Irianiwati Widodo, Dwi Cahyani Ratna Sari, Muhammad Mansyur Romi, Nur Arfian   +5 more
doaj  

Preoperative diagnosis and prediction of hepatocellular carcinoma: Radiomics analysis based on multi-modal ultrasound images

BMC Cancer, 2018
Background This study aims to establish a radiomics analysis system for the diagnosis and clinical behaviour prediction of hepatocellular carcinoma (HCC) based on multi-parametric ultrasound imaging.
Zhao Yao, Yi Dong, Guoqing Wu, Qi Zhang, Daohui Yang, Jin-Hua Yu, Wen-Ping Wang   +6 more
doaj   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source

Unveiling the anti-neoplastic potential of Schistosoma mansoni-derived antigen against breast cancer: a pre-clinical study

European Journal of Medical Research
Background Cancer is a global health concern, with millions of new cases and deaths annually. Recently, immunotherapy has strengthened cancer treatment by harnessing the body's immune system to fight cancer. The search for advanced cancer immunotherapies
Maha Mohamed Eissa, Sonia Rifaat Ahmed Allam, Cherine Adel Ismail, Rasha Abdelmawla Ghazala, Nahla El Skhawy, Inass Ibrahim Ahmed Zaki, Eman Ibrahim El-said Ibrahim   +6 more
doaj   +1 more source

SOX10 Is a Sensitive Marker for Breast and Salivary Gland Adenoid Cystic Carcinoma: Immunohistochemical Characterization of Adenoid Cystic Carcinomas

Breast Cancer: Basic and Clinical Research, 2019
Breast adenoid cystic carcinomas (AdCCs) can pose diagnostic difficulty due to their rarity, particularly on limited biopsy material. Given that these tumors are triple-negative breast cancers with favorable prognosis, accurate diagnosis is critical for ...
Chen Yang, Lingxin Zhang, Souzan Sanati
doaj   +1 more source

Evaluation of the Ki-67 Proliferation Index and Urocortin Expression in Women with Ovarian Endometriomas

Eurasian Journal of Medicine, 2019
Objective: The reasons why endometriosis is more aggressive and invasive in some patients are unknown. Despite the importance of population-based clinically defined risk factors in the prediction of recurrence, biochemical markers obtained from the ...
Serenat Eris Yalcin, Irfan Ocal, Yakup Yalcin, Halime Sen Selim, Melike Demir Caltekin, Huseyin Aydogmus, Sefa Kelekci   +6 more
doaj   +1 more source

EBP2, a novel NPM‐ALK‐interacting protein in the nucleolus, contributes to the proliferation of ALCL cells by regulating tumor suppressor p53

Molecular Oncology, 2021
The oncogenic fusion protein nucleophosmin‐anaplastic lymphoma kinase (NPM‐ALK), found in anaplastic large‐cell lymphoma (ALCL), localizes to the cytosol, nucleoplasm, and nucleolus.
Yuki Uchihara, Kenji Tago, Hiroomi Tamura, Megumi Funakoshi‐Tago   +3 more
doaj   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

NUCLEAR ORGANIZERS IN KI-67 POSITIVE CELLS OF SQUAMOUS CELL LUNG CANCER: CLINICAL MORPHOLOGICAL PARALLELS AND SURVIVAL

Сибирский онкологический журнал, 2016
Purpose: to study argyrophilic proteins associated with nucleolar organizer regions (Ag-NOR proteins) in proliferating cells in relationship between the clinical and morphological parameters and survival in squamous cell lung carcinoma.
D. S. Kobyakov, A. F. Lazarev, Е. L. Lushnikova, L. М. Nepomnyaschikh   +3 more
doaj  

Argyrophilic nucleolar organizer region in MIB-1 positive cells in non-small cell lung cancer: clinicopathological significance and survival

Cancer Biology & Medicine, 2014
Objective To evaluate the relation between argyrophilic nucleolar organizer region (AgNOR)-associated proteins and clinicopathological parameters and survival in non-small-cell lung cancer (NSCLC).
Dmitriy Sergeevich Kobyakov, Ashot Merudzhanovich Avdalyan, Aleksandr Fedorovich Lazarev, Elena Leonidovna Lushnikova, Lev Moiseevich Nepomnyashchikh   +4 more
doaj   +1 more source