Results 31 to 40 of about 137,214 (262)

Sclerosing pneumocytoma with metastasis to the mediastinal and regional lymph nodes

Indian Journal of Pathology and Microbiology, 2018
Sclerosing pneumocytoma (SP) is an uncommon benign tumor, and metastasis of SP has been rarely reported. Here, we report the case of a 26-year-old woman with surgically confirmed SP.
Xiaojun Wang, Lizhi Zhang, Yanfu Wang, Xuzhao Jia, Jiali Wang, Hua Zhang   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Correlations Between DCE MRI and Histopathological Parameters in Head and Neck Squamous Cell Carcinoma

Translational Oncology, 2017
BACKGROUND: Dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) can characterize perfusion and vascularization of tissues. DCE MRI parameters can differentiate between malignant and benign lesions and predict tumor grading. The purpose of this
Alexey Surov, Hans Jonas Meyer, Matthias Gawlitza, Anne-Kathrin Höhn, Andreas Boehm, Thomas Kahn, Patrick Stumpp   +6 more
doaj   +1 more source

Molecular analysis of a chromosomal translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line expressing the Ki-1 antigen. [PDF]

Proceedings of the National Academy of Sciences, 1990
We have studied a translocation, t(9;14)(p13;q32), in a diffuse large-cell lymphoma cell line, KIS-1, that expresses the Ki-1 (CD30) antigen. Molecular cloning of the immunoglobulin heavy-chain locus (IGH) of this cell line revealed an unknown segment linked 5' to IGH.
H, Ohno, T, Furukawa, S, Fukuhara, S Q, Zong, H, Kamesaki, T B, Shows, M M, Le Beau, T W, McKeithan, T, Kawakami, T, Honjo   +9 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells [PDF]

Blood, 1985
Abstract Ki-1 is a monoclonal antibody (raised against a Hodgkin's disease- derived cell line) that, in biopsy tissue affected by Hodgkin's disease, reacts selectively with Reed-Sternberg cells. The expression of Ki-1 antigen has been analyzed by immunocytochemical techniques in a wide range of human tissue and cell samples, including ...
H Stein, DY Mason, J Gerdes, N O'Connor, J Wainscoat, G Pallesen, K Gatter, B Falini, G Delsol, H Lemke, R Schwarting, K Lennert   +11 more
openaire   +4 more sources

Clinical and immunohistochemical study of eight cases with thymic carcinoma

BMC Surgery, 2002
Background Thymic carcinoma is a rare neoplasm with extremely poor prognosis. To evaluate the biological characteristics of thymic carcinoma, we reviewed 8 patients.
Shimizu Tetsuya, Maeda Masayuki, Edagawa Masao, Matsuzaki Yasunori, Tomita Masaki, Hara Masaki, Onitsuka Toshio   +6 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Primary Cutaneous Adenoid Cystic Carcinoma (PCACC) of the Scalp: dermatosurgical approach with favourable outcome

Dermatology Reports, 2022
Although described as early as 1975 as a distinct, rare form of cancer with diverse localization, primary cutaneous adenoid cystic carcinoma (PCACC) remains a mystery and challenge for both clinicians and pathologists.
Georgi Tchernev, Lorraine Joseph Kandathil, Nikhil Oliveira, Jose Carlos Cardoso, James Patterson   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source